<i>Determination of Mixed Venous CO<sub>2</sub> Tensions by Rebreathing</i>

Collier, Clarence R.

doi:10.1152/jappl.1956.9.1.25

Cited by 276 publications

(118 citation statements)

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“…23 End-tidal partial pressure of CO 2 (PCO 2 ) was measured using a rapid-response infrared CO 2 analyzer (PHYSIO-DYNE Instrument, Quogue, NY). End-tidal PCO 2 was used to estimate arterial PCO 2 according to the formula of Jones et al 24 Each subject rebreathed into a 5-L latex bag containing CO 2 and VȮ 2 to permit rapid equilibration with venous PCO 2 .…”

Section: Experimental Test Conditionsmentioning

confidence: 99%

Normal Exercise Blood Pressure Response in African-American Women with Parental History of Hypertension

Bond

Davis

Millis

et al. 2004

The American Journal of the Medical Sciences

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Section: Experimental Test Conditionsmentioning

confidence: 99%

Normal Exercise Blood Pressure Response in African-American Women with Parental History of Hypertension

Bond

Davis

Millis

et al. 2004

The American Journal of the Medical Sciences

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“…Cardiac output, stroke volume and total peripheral vascular resistanceCardiac output was measured non-invasively by using the CO 2 rebreathing technique of Collier [11]. End-tidal partial pressure of CO 2 (PCO 2 ) was measured using a rapid-response infrared CO 2 analyzer (PHYSIO-DYNE Instrument Corp., Quogue, NY).…”

Section: Measurementsmentioning

confidence: 99%

Aerobic Exercise Attenuates an Exaggerated Exercise Blood Pressure Response in Normotensive Young Adult African-American Men

et al. 2002

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An exaggerated exercise blood pressure response (EEBPR) may be associated with an increased risk of hypertension. We hypothesized that aerobic exercise training can decrease EEBPR and the risk for hypertension by decreasing arterial resistance. We studied the effects of aerobic training on the submaximal exercise blood pressure (BP) of eight normotensive young adult AfricanAmerican men with an EEBPR. Subjects were trained on a stationary bicycle at an intensity of 70% peak oxygen uptake (VO 2peak ) for 30 min, three times per week, for 8 weeks. BP, heart rate, cardiac output (CO), stroke volume (SV) and total peripheral vascular resistance (TPR) were measured at rest and during submaximal exercise at a work intensity of 50% VO 2peak . Significance of the training effects were evaluated by comparing the pre-and post-training measures (t-test, p < 0.05). A 15% post-training increase in VO 2peak (34.6 ± 1.4 to 40 ± 1.4 ml/kg/ min) and a 9.5 ml post-training increase in mean resting stroke volume were found. A 16.2 mmHg decrement in mean systolic BP, an 11.5 mmHg decrement in mean diastolic BP, a 120 dyne/s/cm 5 decrement in TPR and a 1.2 l/min increase in CO were detected during the post-training submaximal exercise tests. These results suggest that reductions in TPR may attenuate the EEBPR of normotensive African-American males following an 8-week training regimen of stationary bicycling at 70% VO 2peak . Aerobic exercise training may, therefore, reduce the risk of hypertension in normotensive African-American males by the mechanism of a reduction in TPR. Because of the limited number of subjects, the results of this study should be interpreted cautiously pending confirmation by a larger controlled trial.

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“…The gas volume was determined through a pressure-volume relation during a Valsalva's maneuver according to DuBois et al (1956) by using the body plethysmograph. The rebreathing was performed by using a 5-liters anesthesia bag according to a conventional method (COLLIER, 1956). Since we attempted to confirm reliabilities of avD0 2 and Q values, too, both 02 and C02 concentrations were recorded continuously during the rebreathing.…”

Section: Andmentioning

confidence: 99%

“…Especially since the development of an infrared C02 analyzer by FOWLER (1949), many papers have appeared concerning the cardiac output measurement using C02 rebreathing. COLLIER (1956) measured the oxygenated venous Pco2 (ox-P02) by rebreathing hypercapnic air. DEFARES et al (1961) elaborated an extrapolation method to estimate the ox-P0, from a CO,-curve during the rebreathing.…”

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confidence: 99%

A new indirect method for measuring arteriovenous O2 content difference and cardiac output from O2 and CO2 concentrations by rebreathing air.

et al. 1984

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A new indirect method for measuring the arteriovenous 02 content difference (avDo 2) was developed. The avDo 2 was calculated by dividing the gradient of the C02 dissociation curve by that of a gas exchange ratio against Pco2. The latter slope was obtained from 02 and C02 concentrations in rebreathing air. The validity of the method was tested preliminarily in human subjects by comparing the cardiac output calculated from avDo 2 and 02 uptake (o2) with that measured hitherto by other authors, and then in dogs by comparing the calculated avDo, with the measured value. In the dog experiments, the rebreathing was performed 7 times in each of 7 dogs. Immediately after the rebreathing arterial and mixed venous blood were sampled and analyzed for avDo2. For each rebreathing period the avDo, was calculated by using the C02 dissociation curve obtained in the individual dogs. The correlation coefficient between the measured and calculated avDo2 was 0.87, demonstrating reasonable validity of the method. The Vo2 was further measured from the time interval during which a known amount of pure 02 was consumed. Then, the cardiac output was calculated by dividing the Vo2 by the measured and calculated avDo2. The correlation coefficient between the respective cardiac output values was 0.88, indicating the reliability of using the calculated avDo 2.

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Determination of Mixed Venous CO₂ Tensions by Rebreathing

Cited by 276 publications

References 0 publications

Normal Exercise Blood Pressure Response in African-American Women with Parental History of Hypertension

Normal Exercise Blood Pressure Response in African-American Women with Parental History of Hypertension

Aerobic Exercise Attenuates an Exaggerated Exercise Blood Pressure Response in Normotensive Young Adult African-American Men

A new indirect method for measuring arteriovenous O2 content difference and cardiac output from O2 and CO2 concentrations by rebreathing air.

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Determination of Mixed Venous CO2 Tensions by Rebreathing

Cited by 276 publications

References 0 publications

Normal Exercise Blood Pressure Response in African-American Women with Parental History of Hypertension

Normal Exercise Blood Pressure Response in African-American Women with Parental History of Hypertension

Aerobic Exercise Attenuates an Exaggerated Exercise Blood Pressure Response in Normotensive Young Adult African-American Men

A new indirect method for measuring arteriovenous O2 content difference and cardiac output from O2 and CO2 concentrations by rebreathing air.

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Determination of Mixed Venous CO₂ Tensions by Rebreathing