De novoassembly of the selfishtsupergene reveals a deleterious evolutionary trajectory
Jan-Niklas Runge,
Kristian Ullrich,
Anna K. Lindholm
Abstract:Supergenes are linked clusters of DNA that are transmitted together due to rare or absent recombination. They undergo co-adaptation, allowing evolution to work on several genes to refine complex phenotypes, giving supergenes a competitive edge. Yet, due to their lack of recombination, supergenes are susceptible to deterioration as they cannot efficiently purge deleterious DNA. Few examples outside of sex chromosomes have been available for study. Here, we present the first assembly of the t haplotype, a 33.4 M… Show more
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