Clostridium hastiformebacteraemia secondary to pyometra in a 64-year-old woman

Abstract

The Gram-negative, rod-shaped, anaerobe bacteria Tissierella praeacuta was first described in 1908 by Tissier. However, during the past decade, Clostridium hastiforme has been recognised as a later synonym of T. praeacuta. C. hastiforme/T. praeacuta has only rarely been described in previous literature as a cause of human infection. We present here a case report of C. hastiforme/T. praeacuta bacteraemia secondary to pyometra in a 64-year-old woman with a history of multiple sclerosis and an intrauterine device inserted three decades earlier. C. hastiforme/T. praeacuta was isolated from blood as well as pus from the site of infection. The patient was cured with a combination of drainage and antibiotic therapy.

Tissierella praeacuta Bacteremia Associated With Acute on Chronic Osteomyelitis: A Case Report

“…Tissierella bacteremia has been previously reported to co-infect patients with chronic infections such as calcaneal osteomyelitis in a diabetic patient [ 4 ] and sacral decubitus ulcer [ 3 ], successfully treated with beta-lactams. Other reported cases include knee arthroplasty, pyonephrosis with communicating liver abscess [ 5 ], brain abscess secondary to otitis media in a child [ 6 ], sepsis secondary to colon adenocarcinoma [ 7 ], eyelid gas gangrene [ 8 ], and pyometra secondary to an intrauterine device [ 9 ]. Most cases are successfully treated with beta-lactams, although susceptibility to rifampicin and chloramphenicol is also reported.…”