<i>Chlamydia Psittaci</i>, Causative Agent of Avian Chlamydiosis and Human Psittacosis: Risk Assessment and Biosafety Recommendations for Laboratory use

Dickx, Veerle; Droogenbroeck, Caroline Van; Vaerenbergh, Bernadette Van; Herman, Philippe; Vanrompay, Daisy

doi:10.1177/153567601201700206

Cited by 4 publications

(3 citation statements)

References 37 publications

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“…In conclusion, it is very important, above all during the SARS-COV-2 pandemic, not to dwell on the suspected viral pneumonia (like SARS-COV-2 , RSV, Adenovirus, Influenza, and Parainfluenza viruses , etc.) but to investigate also the environmental anamnesis to prevent other serious respiratory diseases with even worse prognoses [ 31 , 32 , 34 , 35 ].…”

Section: Discussionmentioning

confidence: 99%

A pediatric case of Chlamydia psittaci caused severe Acute Respiratory Distress Syndrome (ARDS) in Italy

Marchese,

Paviglianiti

et al. 2023

Ital J Pediatr

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Background This case of psittacosis in children, is the first described in literature, in Italy. This respiratory infection can be transmitted to humans from the inhalation of respiratory secretions, feces and plumage aerosol of infected birds (and other animals). Usually it can have an asymptomatic or paucisymptomatic course, and the onset is often flu-like, but in this case the child risked his life for a severe respiratory failure. This report is unique because in children psittacosis is rare, and always misdiagnosed, or could cause a delayed diagnosis because of lack of awareness among the paediatricians and physicians. Furthermore, psittacosis enters a differential diagnosis with SARS-COV2 infection because both diseases may determine dyspnea and atypical pneumonia, up to acute respiratory failure. Case presentation This clinical case talks about a three-and-a-half-year-old male child affected by psittacosis (or ornithosis), with severe dyspnea and systemic symptoms who required oro-tracheal intubation for acute respiratory failure. The child had slept in a room at home, with some recently bought parrots affected by psittacosis. Initially the child was treated with empiric antibiotic therapy (i.v.ceftriaxone and teicoplanin), but after having isolated the DNA of the germ “Chlamydia psittaci” in both serological and through bronchoalveolar lavage (BAL), he was treated with targeted antibiotic therapy: tetracyclines (doxicillin). Conclusions Psittacosis is an extremely contagious disease, caused by an intracellular germ, called “Chlamydia psittaci”, a Gram-negative bacterium, transmitted to humans in particular by infected birds, responsible for atypical pneumonia, with acute and chronic respiratory symptoms, sometimes with multi-organ failure and disseminated intravascular coagulation. Even if it is a rare respiratory disease among children, a good doctor must think about psittacosis as cause of respiratory symptoms (and not only flu or SARS-COV2), above all through a correct medical history, in order to provide a targeted antibiotic therapy. An interesting case of psittacosis in a child is being reported here, which has been treated successfully with doxycillin.

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Section: Discussionmentioning

confidence: 99%

A pediatric case of Chlamydia psittaci caused severe Acute Respiratory Distress Syndrome (ARDS) in Italy

Marchese,

Paviglianiti

et al. 2023

Ital J Pediatr

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“…Individuals who are routinely in close contact with birds, such as birdkeepers, poultry workers, and veterinarians, are at a high risk of infection. However, passing or transient contact with feral pigeons results in many (40%) of reported cases in humans [6][7][8].…”

Section: Introductionmentioning

confidence: 99%

Investigation of Lethal Concurrent Outbreak of Chlamydiosis and Pigeon Circovirus in a Zoo

Chen

Teng

Shih

et al. 2021

Animals

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During the spring, an outbreak of sudden death involving 58 birds occurred in a zoo. Histopathological examinations revealed variable numbers of intracytoplasmic basophilic microorganisms in the macrophages, hepatocytes, and renal epithelium of most birds, along with occasional botryoid intracytoplasmic inclusion bodies within histiocytes in the bursa of Fabricius. Based on the results of histopathological examinations, immunohistochemical staining, transmission electron microscopy, and polymerase chain reactions, genotype B Chlamydia psittaci infection concurrent with pigeon circovirus (PiCV) was diagnosed. A retrospective survey, including two years before the outbreak and the outbreak year, of C. psittaci and PiCV infections of dead birds in the aviaries, revealed that the outbreak was an independent episode. The findings of this study indicate that concurrent infection with C. psittaci and PiCV might lead to lethal outbreaks of chlamydiosis, particularly Streptopelia orientalis. In addition, persistently monitoring both pathogens and identifying potential PiCV carriers or transmitters might also help prevent lethal disease outbreaks.

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“…En el mundo se han reportado grandes tasas de morbilidad- mortalidad humana 7 . La transmisión zoonótica de C. psittaci se produce por contacto con secreciones respiratorias, tejidos o excrementos provenientes de las aves infectadas; en los humanos, causa la enfermedad denominada psitacosis 7 , 8 . Esta infección afecta principalmente el sistema respiratorio y puede manifestarse por un cuadro clínico leve de tipo resfriado, complicarse como una neumonía atípica o diseminarse a otros órganos, causando una enfermedad sistémica que en algunos casos conduce a la muerte 9 .…”

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Seropositividad de Chlamydia psittaci en trabajadores expuestos a aves y revisión de la literatura: evidencia de circulación en Antioquia

Ossa-Giraldo,

Úsuga-Perilla,

Correa

et al. 2023

biomedica

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Introducción. La psitacosis es una enfermedad zoonótica causada por Chlamydia psittaci. Esta bacteria es catalogada como un agente con potencial bioterrorista y ha causado múltiples brotes en trabajadores con exposición laboral a aves en diferentes lugares del mundo. En Colombia, no se hace seguimiento epidemiológico de la infección y existe una gran brecha en el conocimiento.Objetivos. Determinar la frecuencia de anticuerpos contra C. psittaci en trabajadores con exposición laboral a aves y sus factores asociados. Además, revisar la literatura en relación con los estudios sobre el tema realizados en Colombia.Materiales y métodos. Se llevó a cabo un estudio descriptivo, transversal, con intención analítica, en trabajadores en contacto con aves y se revisó la literatura científica relacionada en Colombia. Se detectaron anticuerpos IgM e IgG contra C. psittaci en suero por microinmunofluorescencia. La descripción de las características sociodemográficas y de exposición se hizo con frecuencias y medidas de resumen. Se exploraron factores asociados por análisis bivariados y multivariados. La revisión de la literatura científica y gris se hizo con búsqueda estructurada.Resultados. Se analizaron 54 trabajadores en contacto con aves y se encontró una prevalencia de anticuerpos del 31,5 %. El ejercer funciones de sacrificio y faenado de las aves sin ser médico veterinario fue un factor de riesgo para la presencia de anticuerpos. Solo se encontraron cuatro estudios previos sobre C. psittaci hechos en Colombia.Conclusiones. Este estudio constituye la primera evidencia de la circulación de C. psittaci en trabajadores en contacto con aves en Antioquia y el segundo reporte en el país. Estos hallazgos aportan desde la salud pública a la estrategia One Health.

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Chlamydia Psittaci, Causative Agent of Avian Chlamydiosis and Human Psittacosis: Risk Assessment and Biosafety Recommendations for Laboratory use

Cited by 4 publications

References 37 publications

A pediatric case of Chlamydia psittaci caused severe Acute Respiratory Distress Syndrome (ARDS) in Italy

A pediatric case of Chlamydia psittaci caused severe Acute Respiratory Distress Syndrome (ARDS) in Italy

Investigation of Lethal Concurrent Outbreak of Chlamydiosis and Pigeon Circovirus in a Zoo

Seropositividad de Chlamydia psittaci en trabajadores expuestos a aves y revisión de la literatura: evidencia de circulación en Antioquia

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