<i>Chlamydia</i> in cases of bovine abortion in Ireland

Wheelhouse, Nicholas; Longbottom, David; O'Donovan, Jim

doi:10.1136/vr.g3567

Cited by 5 publications

(8 citation statements)

References 6 publications

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“…The identification of CROs in a relatively large percentage of the bovine placental samples tested seven of 77 (9 per cent) is indicative of a potential role for these organisms in undiagnosed bovine abortions in England and Wales. The level of incidence observed during this study is highly consistent with those observed in other studies carried out within Scotland (Wheelhouse and others 2011), Ireland (Wheelhouse and others 2014) and Switzerland (Borel and others 2007, Ruhl and others 2009, Blumer and others 2011). Suckler herds appeared to be over‐represented in the Chlamydia ‐positive samples and while conclusions are difficult to draw from such a small dataset, the effects of production system perhaps needs to be investigated further.…”

Section: Case Top Blast Match (% Similarity) Other Identified Infectisupporting

confidence: 92%

Evidence of members of the Chlamydiales in bovine abortions in England and Wales

et al. 2015

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Section: Case Top Blast Match (% Similarity) Other Identified Infectisupporting

confidence: 92%

Evidence of members of the Chlamydiales in bovine abortions in England and Wales

et al. 2015

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“…185 Parachlamydia has been related to bovine abortion cases and to a lesser extent caprine and ovine abortion in Switzerland, England, Scotland, Ireland, Hungary, and Tunisia. 9,18,23,41,82,139,140,186,188,190 Parachlamydial cases revealed necrotizing or purulent to necrotizing placentitis sometimes with vasculitis in common. The presence of a nonsuppurative interstitial pneumonia in fetal lungs was also reported in relation to parachlamydial infection but IHC remained negative.…”

Section: Crb Clo With Proven Pathogenic Potentialmentioning

confidence: 99%

A Review on Chlamydial Diseases in Animals: Still a Challenge for Pathologists?

2018

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Chlamydiae have a worldwide distribution causing a wide range of diseases in human hosts, livestock, and companion animals as well as in wildlife and exotic species. Moreover, they can persist in their hosts as asymptomatic infections for extended periods of time. The introduction of molecular techniques has revolutionized the Chlamydia field by expanding the host range of known chlamydial species but also by discovering new species and even new families of bacteria in the broader order Chlamydiales. The wide range of hosts, diseases, and tissues affected by chlamydiae complicate the diagnosis such that standard diagnostic approaches for these bacteria are rare. Bacteria of the Chlamydiales order are small and their inclusions are difficult to detect by standard microscopy. With the exception of avian and ovine chlamydiosis, macroscopic and/or histologic changes might not be pathognomic or indicative for a chlamydial infection or even not present at all. Moreover, detection of chlamydial DNA in specimens in the absence of other methods or related pathological lesions questions the significance of such findings. The pathogenic potential of the majority of recently identified Chlamydia-related bacteria remains largely unknown and awaits investigation through experimental or natural infection models including histomorphological characterization of associated lesions. This review aims to summarize the historical background and the most important developments in the field of animal chlamydial research in the past 5 years with a special focus on pathology. It will summarize the current nomenclature, present critical thoughts about diagnostics, and give an update on chlamydial infections in domesticated animals such as livestock, companion animals and birds, as well as free-ranging and captive wild animals such as reptiles, fish, and marsupials.

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“…A further retrospective study analysing pooled tissues from undiagnosed cases of bovine abortion identified 26 % of the samples as positive for Chlamydia-related organisms, however, in addition to Parachlamydia, Rhabdochlamydia was also identified as associated with bovine abortion for the first time [36]. The high level of detection of 18-26 % in these initial Swiss and UK studies has been confirmed in subsequent studies carried out on placental samples from Scotland by immunohistochemistry [37] and from placental and fetal tissue samples from Ireland by real-time PCR [38]. There is also some evidence to suggest a degree of regional variation in the prevalence of the organism in cases of bovine abortion, with a more recent Swiss study demonstrating a lower apparent prevalence rate of 13.4 % [27] compared with the 18.4 % observed previously within the same country [28,29].…”

Section: Identification Prevalence and Pathogenesismentioning

confidence: 72%

“…However, most recently a highly sensitive and quantifiable genus-specific real-time PCR protocol, which is compatible with direct sequencing, has been developed [72]. This has been successfully used in recent studies on ruminants [38,39].…”

Section: Diagnosismentioning

confidence: 99%

Chlamydia-related Organisms: Infection in Ruminants and Potential for Zoonotic transmission

Wheelhouse

Longbottom

2015

Curr Clin Micro Rpt

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The chlamydiae are a diverse group of obligate intracellular Gram-negative bacteria that are known to infect a wide variety of host species and are responsible for a wide range of diseases in animals and man. Studies of human disease first provided evidence for the disease-causing potential of Chlamydia-related bacteria, however there is now increasing evidence that a number of these organisms may also be the causative agents for a number of pathogenic conditions of ruminants that had previously remained undiagnosed. The aim of this review is to draw together the evidence for the role of the newly emerging chlamydial infections in livestock disease.

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Chlamydia in cases of bovine abortion in Ireland

Cited by 5 publications

References 6 publications

Evidence of members of the Chlamydiales in bovine abortions in England and Wales

Evidence of members of the Chlamydiales in bovine abortions in England and Wales

A Review on Chlamydial Diseases in Animals: Still a Challenge for Pathologists?

Chlamydia-related Organisms: Infection in Ruminants and Potential for Zoonotic transmission

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