<i>Cdc2</i>
            Protein Kinase: Structure–Function Relationships

Marcote, María Jesús; Pagano, Michele; Draetta, Giulio

doi:10.1002/9780470514320.ch4

“…Based upon the catalytic activity, PKs (protein kinases) are divided into many groups e.g. the AGC group includes three kinds of kinases, PKA, PKG and PKC; ARK group, the ribosomal S6 kinase, NDR (Marcote et al, 1992;Dickman and Yarden, 1999;Franchi et al, 2005). The CK1 is a small but important group in eukaryotes having CK1 protein family; the CAMK group has CAMK1 and CAMK2 protein kinases.…”

Section: O N L I N E F I R S T a R T I C L Ementioning

confidence: 99%

Co-Treatment of Caffeic Acid Phenethyl Ester with Chitosan Nanoparticles Inhibits DNA Methylation in HepG2 Cells

Alzahani¹

2024

PJZ

2

0

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Protein Kinase C (PKC) and tubulin homologs are present in all eukaryotes and play significant role in growth, development and cell differentiation through phosphorylation and de-phosphorylation of other proteins. In this study, we have amplified PKC and beta tubulin homolog bml gene from six strains and F3 and F4 generations of Sordaria fimicola collected from the Evolution Canyon-1. Sequenced products of 464 bp of tubulin gene and 548 bp for PKC gene were aligned to observe the genetic variations between the eight parental strains of S. fimicola and reference sequence of S. fimicola. Total six polymorphic sites were observed in case of tubulin gene out of which 5 sites were common among strains isolated from the s-slope of Evolution Canyon (EC). Genetic variations in four nucleotides were observed for PKC gene i.e. C (150) T; C (186) A; C (429) G and T (521) A which were common for S1, S2 and S3 strains, while point mutation C (497) G was detected only in S2 and S3 strains. Post translational modifications (PTMs) of both proteins were predicted and compared with the reference sequences of Neurospora crassa and Sordaria macrospora by using different PTMs predictor servers. Phosphorylation and glycosylation in different species of Sordaria as well as N. crassa was calculated on Serine (S), Tyrosine (Y) and Threonine (T) residues by NetPhos and YinOYang.

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“…Based upon the catalytic activity, PKs (protein kinases) are divided into many groups e.g. the AGC group includes three kinds of kinases, PKA, PKG and PKC; ARK group, the ribosomal S6 kinase, NDR (Marcote et al, 1992;Dickman and Yarden, 1999;Franchi et al, 2005). The CK1 is a small but important group in eukaryotes having CK1 protein family; the CAMK group has CAMK1 and CAMK2 protein kinases.…”

Section: O N L I N E F I R S T a R T I C L Ementioning

confidence: 99%

Effect of Acetone Extract of Salvia miltiorrhiza Bunge on Feeding Selection Behavior of Diamondback Moth Larvae

Li¹

2024

PJZ

0

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Protein Kinase C (PKC) and tubulin homologs are present in all eukaryotes and play significant role in growth, development and cell differentiation through phosphorylation and de-phosphorylation of other proteins. In this study, we have amplified PKC and beta tubulin homolog bml gene from six strains and F3 and F4 generations of Sordaria fimicola collected from the Evolution Canyon-1. Sequenced products of 464 bp of tubulin gene and 548 bp for PKC gene were aligned to observe the genetic variations between the eight parental strains of S. fimicola and reference sequence of S. fimicola. Total six polymorphic sites were observed in case of tubulin gene out of which 5 sites were common among strains isolated from the s-slope of Evolution Canyon (EC). Genetic variations in four nucleotides were observed for PKC gene i.e. C (150) T; C (186) A; C (429) G and T (521) A which were common for S1, S2 and S3 strains, while point mutation C (497) G was detected only in S2 and S3 strains. Post translational modifications (PTMs) of both proteins were predicted and compared with the reference sequences of Neurospora crassa and Sordaria macrospora by using different PTMs predictor servers. Phosphorylation and glycosylation in different species of Sordaria as well as N. crassa was calculated on Serine (S), Tyrosine (Y) and Threonine (T) residues by NetPhos and YinOYang.

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“…Based upon the catalytic activity, PKs (protein kinases) are divided into many groups e.g. the AGC group includes three kinds of kinases, PKA, PKG and PKC; ARK group, the ribosomal S6 kinase, NDR (Marcote et al, 1992;Dickman and Yarden, 1999;Franchi et al, 2005). The CK1 is a small but important group in eukaryotes having CK1 protein family; the CAMK group has CAMK1 and CAMK2 protein kinases.…”

Section: O N L I N E F I R S T a R T I C L Ementioning

confidence: 99%

Genetic Diversity and its Impact on Post Translational Modifications of PKC and bml-Beta Tubulin Homolog Proteins in Different Species and Strains of Sordaria

Ahsan¹,

Arif²,

Nazir³

et al. 2023

PJZ

0

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Protein Kinase C (PKC) and tubulin homologs are present in all eukaryotes and play significant role in growth, development and cell differentiation through phosphorylation and de-phosphorylation of other proteins. In this study, we have amplified PKC and beta tubulin homolog bml gene from six strains and F3 and F4 generations of Sordaria fimicola collected from the Evolution Canyon-1. Sequenced products of 464 bp of tubulin gene and 548 bp for PKC gene were aligned to observe the genetic variations between the eight parental strains of S. fimicola and reference sequence of S. fimicola. Total six polymorphic sites were observed in case of tubulin gene out of which 5 sites were common among strains isolated from the s-slope of Evolution Canyon (EC). Genetic variations in four nucleotides were observed for PKC gene i.e. C (150) T; C (186) A; C (429) G and T (521) A which were common for S1, S2 and S3 strains, while point mutation C (497) G was detected only in S2 and S3 strains. Post translational modifications (PTMs) of both proteins were predicted and compared with the reference sequences of Neurospora crassa and Sordaria macrospora by using different PTMs predictor servers. Phosphorylation and glycosylation in different species of Sordaria as well as N. crassa was calculated on Serine (S), Tyrosine (Y) and Threonine (T) residues by NetPhos and YinOYang.

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Cdc2 Protein Kinase: Structure–Function Relationships

Cited by 5 publications

References 65 publications

Co-Treatment of Caffeic Acid Phenethyl Ester with Chitosan Nanoparticles Inhibits DNA Methylation in HepG2 Cells

Co-Treatment of Caffeic Acid Phenethyl Ester with Chitosan Nanoparticles Inhibits DNA Methylation in HepG2 Cells

Effect of Acetone Extract of Salvia miltiorrhiza Bunge on Feeding Selection Behavior of Diamondback Moth Larvae

Genetic Diversity and its Impact on Post Translational Modifications of PKC and bml-Beta Tubulin Homolog Proteins in Different Species and Strains of Sordaria

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