Campylobacter jejuniandCampylobactercoliin Children With Acute Diarrhea in Health Centers of Hamadan, Iran

Abstract

Background: Enteritis caused by Campylobacter is considered as the most common acute bacterial diarrhea around the world. In most cases, infection occurs as a result of consuming contaminated water or food, especially raw meat of fowls. Objectives: The purpose of the present study was to determine the prevalence and antibiotic resistance of campylobacter species among pediatrics of Hamadan city, Iran. Patients and Methods: A total of 120 stool samples from children less than 10 years old were examined from January 2013 to December 2014 in Hamadan, Iran. The samples were incubated in Campy-Thio enrichment medium for 1 -2 hours and then cultured on a specific medium; after that, the suspected colonies were analyzed for Campylobacter spp. identification by conventional tests. The identified species by biochemical methods were confirmed by polymerase chain reaction (PCR). Antimicrobial susceptibility testing was performed by disk agar diffusion (DAD) method. Results: Twelve (10%) Campylobacter spp. from 120 stool samples were isolated including C. coli and C. jejuni. In the antibiotic susceptibility test, the most frequent resistance was observed to ciprofloxacin 8 (88.8%), followed by 7 (77.7%) resistant strains to tetracycline, 7 (77.7%) to erythromycin, 6 (66.6%) to clindamycin, 5 (55.5%) to meropenem, 4 (44.4%) to gentamicin, 3 (33.3%) to nalidixicacid and only 1 (11.1%) to chloramphenicol. Conclusions: Campylobacter is responsible for some important clinical problems such as enteritis and is also associated with meningitis and hemolytic-uremic syndrome. It is imperative to monitor the prevalence and antibiotic resistance of Campylobacter spp. as well as other the zoonotic bacteria.

Global epidemiology of campylobacteriosis and the impact of COVID-19

“…Around the same time between 2013-2014 in Hamadan, 10% (12/120) of the diarrheal stool samples from children less than 10 years old had Campylobacter isolated. In Central Iran, 33% (76/230) diarrheal stools from children were PCR positive for C. jejuni in 2015, among which most of the infections occurred in the age group of 1-3 years ( Rastyani et al., 2015 ; Abbasi et al., 2019 ). Campylobacter infection was found to be more prevalent in girls in Semnan, contrary to that of Central Iran ( Mazaheri et al., 2016 ; Abbasi et al., 2019 ).…”

Contact with poultry and animals increases risk of Campylobacter infections in adults of Ardabil province, Iran

“…The 6% and 5.7% prevalence of Campylobacter species in Ardabil province was obtained in the present research by PCR and culture methods, respectively. Previous findings in some cities of Iran indicated 12.4% in Semnan, (3) 8% in Tehran, (35) 10% in Hamedan (36) and 6.4% in Zanjan. (37) Differences in prevalence rates probably are related to pathogenic agents or living conditions in different regions.…”

Prevalence of Fluoroquinolone-Resistant Campylobacter Species in Iran: A Systematic Review and Meta-Analysis

“…The characteristics of the 34 included studies are summarized in Tables 1 – 3 . The main data was extracted from 3 studies from Ahvaz [ 11 – 13 ], 2 studies from Hamadan [ 14 , 15 ], 4 studies from Isfahan [ 16 – 19 ], 1 study from Kerman [ 20 ], 1 study from Kurdistan [ 21 ], 2 studies from Mashhad [ 22 , 23 ], 1 study from Mazandaran and Golestan [ 24 ], 1 study from Rafsanjan [ 25 ], 5 studies from Shahrekord [ 13 , 18 , 26 – 28 ], 2 studies from Semnan [ 29 , 30 ], 4 studies from Shiraz [ 31 – 34 ], 8 studies from Tehran [ 35 – 42 ], 2 studies from Tonekabon [ 34 , 43 ], 1 study from Yazd [ 19 ], and 1 study from Zahedan [ 44 ]. Disk diffusion, E -test, and agar dilution were the most common methods used to evaluate antibiotic-resistant Campylobacter species in Iran (Tables 1 – 3 ).…”