<i>Brucella Suis</i>Biovar 1 in Naturally Infected Cattle: A Bacteriological, Serological, and Histological Study

Ewalt, Darla R.; Payeur, Janet B.; Rhyan, Jack C.; Geer, Patricia L.

doi:10.1177/104063879700900414

Cited by 58 publications

(42 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Indeed, B. abortus abortions in sheep, goats and pigs have been seldom reported in the past and not further documented in recent decades. Although B. suis biovars 1 and 3 isolations from cattle have been reported in the Americas and Australia, B. suis biovars 1 and 3 abortions have never been documented in cattle [24,33]. B. suis biovar 2 is a self limited infection in cattle [42].…”

Section: Discussionmentioning

confidence: 97%

From the discovery of the Malta fever?s agent to the discovery of a marine mammal reservoir, brucellosis has continuously been a re-emerging zoonosis

et al. 2005

View full text Add to dashboard Cite

-Brucellosis is not a sustainable disease in humans. The source of human infection always resides in domestic or wild animal reservoirs. The routes of infection are multiple: foodborne, occupational or recreational, linked to travel and even to bioterrorism. New Brucella strains or species may emerge and existing Brucella species adapt to changing social, cultural, travel and agricultural environment. Brucella melitensis is the most important zoonotic agent, followed by Brucella abortus and Brucella suis. This correlates with the fact that worldwide, the control of bovine brucellosis (due to B. abortus) has been achieved to a greater extent than the control of sheep and goat brucellosis (due to B. melitensis), these latter species being the most important domestic animals in many developing countries. The long duration and high cost of treatment of human brucellosis reduces the efficacy of the therapy. There is no human vaccine for brucellosis and the occurrence of brucellosis is directly linked to the status of animal brucellosis in a region. In this context, the Word Health Organization has defined the development of a human vaccine, besides the implementation of control and eradication programs in animals, as a high priority. The pathogenicity for humans of B. suis biovars 1, 3 and 4 is well established, whereas B. suis biovar 2 seems to be less pathogenic. Indeed, although hunters and pig farmers have repeatably experienced infectious contact with B. suis biovar 2 (found in wild boar and outdoor-rearing pigs in Europe), isolation of B. suis biovar 2 from human samples have only been seldom reported. Marine mammal brucellosis, due to two new proposed Brucella species i.e. B. cetaceae and B. pinnipediae, represents a new zoonotic threat but the pathogenicity for humans of the different Brucella species found in cetaceans and pinnipeds still has to be clearly established.Brucella / animal and human brucellosis / zoonoses / domestic and wildlife reservoir

show abstract

Section: Discussionmentioning

confidence: 97%

From the discovery of the Malta fever?s agent to the discovery of a marine mammal reservoir, brucellosis has continuously been a re-emerging zoonosis

et al. 2005

View full text Add to dashboard Cite

show abstract

“…Brucella suis (mostly biovars 1, 2 and 3) also infects cattle, but such infections are usually not associated with clinical signs (19). Pathogenesis of B. abortus in cattle has been thoroughly reviewed (20).…”

Section: Insights Into the Pathology And Clinical Manifestations Of Bmentioning

confidence: 99%

The quest for a true One Health perspective of brucellosis

Godfroid¹,

DeBolle²,

Roop³

et al. 2014

Rev. Sci. Tech. OIE

View full text Add to dashboard Cite

SummaryOne Health is an interdisciplinary collaboration that aims at mitigating risks to human health arising from microorganisms present in non-human animal species, which have the potential to be transmitted and cause disease in humans. Different degrees of scientific collaboration and sectoral integration are needed for different types of zoonotic diseases, depending on the health and associated economic gains that can be expected from a One Health approach. Indeed, mitigating zoonotic risks related to emerging diseases with pandemic potential is different from mitigating risks related to endemic zoonotic diseases like brucellosis. Likewise, management of brucellosis at the wildlife-livestock interface in wildlife conservation areas is in essence different from mitigating transmission of a given Brucella species within its preferential host species, which in turn is different from mitigating the spillover of a given Brucella species to non-preferential host species, humans included. Brucellosis economic models often oversimplify and/or wrongly assess transmission between reservoir hosts and spillover hosts. Moreover, they may not properly value non-market outcomes, such as avoidance of human disease, consumer confidence and conservation biology issues. As a result, uncertainty is such that the economic predictions of these models can be questionable. Therefore, understanding the infection biology of Brucella species is a prerequisite. This paper reviews and highlights important features of the infection biology of Brucella species and the changing epidemiology of brucellosis that need to be integrated into a true One Health perspective of brucellosis.

show abstract

“…35 In addition to the infection of domestic swine with B. suis, feral swine are also responsible for infecting cattle with B. suis. 9 Because of their popularity as a game species and the widespread distribution of brucellosis within these populations, feral swine are also a significant threat for zoonotic infections. 27 …”

Section: Introductionmentioning

confidence: 99%

Diagnostic Characterization of a Feral Swine Herd Enzootically Infected withBrucella

et al. 2007

View full text Add to dashboard Cite

Abstract. Eighty feral swine were trapped from a herd that had been documented to be seropositive for Brucella and which had been used for Brucella abortus RB51 vaccine trials on a 7,100-hectare tract of land in South Carolina. The animals were euthanized and complete necropsies were performed. Samples were taken for histopathology, Brucella culture, and Brucella serology. Brucella was cultured from 62 (77.5%) animals. Brucella suis was isolated from 55 animals (68.8%), and all isolates were biovar 1. Brucella abortus was isolated from 28 animals (35.0%), and isolates included field strain biovar 1 (21 animals; 26.3%), vaccine strain Brucella abortus S19 (8 animals, 10.0%), and vaccine strain Brucella abortus RB51 (6 animals, 7.5%). Males were significantly more likely to be culture positive than females (92.9% vs. 60.6%). Thirty-nine animals (48.8%) were seropositive. Males also had a significantly higher seropositivity rate than females (61.9% vs. 34.2%). The relative sensitivity rates were significantly higher for the standard tube test (44.6%) and fluorescence polarization assay (42.6%) than the card agglutination test (13.1%). Lesions consistent with Brucella infection were commonly found in the animals surveyed and included inflammatory lesions of the lymph nodes, liver, kidney, and male reproductive organs, which ranged from lymphoplasmacytic to pyogranulomatous with necrosis. This is the first report of an apparent enzootic Brucella abortus infection in a feral swine herd suggesting that feral swine may serve as a reservoir of infection for Brucella abortus as well as Brucella suis for domestic livestock.

show abstract

Brucella SuisBiovar 1 in Naturally Infected Cattle: A Bacteriological, Serological, and Histological Study

Cited by 58 publications

References 4 publications

From the discovery of the Malta fever?s agent to the discovery of a marine mammal reservoir, brucellosis has continuously been a re-emerging zoonosis

From the discovery of the Malta fever?s agent to the discovery of a marine mammal reservoir, brucellosis has continuously been a re-emerging zoonosis

The quest for a true One Health perspective of brucellosis

Diagnostic Characterization of a Feral Swine Herd Enzootically Infected withBrucella

Contact Info

Product

Resources

About