Brassica rapa L. (Tibetan turnip) prevents sleep-deprivation induced cognitive deficits via the inhibition of neuroinflammation and mitochondrial depolarization

Abstract

Brassica rapa L., has substantial protective effects against sleep deprivation-induced learning and memory deficits, as well as other deleterious effects (ie., neuroinflammation) via AMPK/PPAR-γ signaling pathways.

A combined effect of fish-originated collagen peptides and caffeine on the cognitive function of sleep-deprived mice

“…After adaptation for 7 days, they were divided into 7 groups ( n = 10) randomly (five mice each cage): the Con group (saline); the SD group (saline); the Pos group (caffeine, 10 mg per kg per bw (ref. 20 and 21)) and the C&F-fed mice groups, which were further classified in the low-dose groups (10 mg per kg per bw caffeine combined with 100 mg per kg bw FCP) for a day (Day_L group) or a week (Week_L group), and the high-dose groups (20 mg per kg per bw caffeine combined with 200 mg per kg per bw FCP) for a day (Day_H group) or a week (Week_H group). 22 As shown in Fig.…”

“…The Con mice were provided regular rest, while mice in the other groups were subjected to the Automated Sleep Deprivation System for 48 h as previously described. 21 Then, they were all employed for behavioral tests and biochemical parameters. Animal experiments of the present study were approved by the Ethics Committee of EACJN (no.…”

Urolithin A Ameliorates Athletic Ability and Intestinal Microbiota in Sleep Deprivation from the Perspective of the Gut‐Muscle Axis

“…Subsequently, a rotating metal bar with timed movements (5 rpm) was employed to sweep the entire cage bottoms smoothly, thereby preventing the mice from falling asleep during the 48-h SD period as previously described. [22]…”

Ginsenoside Rg1 Attenuates Chronic Sleep Deprivation-Induced Hippocampal Mitochondrial Dysfunction and Improves Memory by the AMPK-SIRT3 Pathway

“…5,6 Emerging evidence suggests that SD induces hippocampal mitochondrial dysfunction and oxidative process-related neurobiological changes, crucial factors in learning and memory impairment. 7,8 Prolonged lack of sleep leads to an imbalance between reactive oxygen species (ROS) production and antioxidant defenses, resulting in oxidative stress (OS). 9 This oxidative state impairs mitochondrial function, disrupting energy production, and cellular processes.…”