Bacillus Anthracis

Anthrax

“…Attenuated vaccine strains carry only 1 of the 2 plasmids, such as the Sterne strain that contains only pXO1 and the Pasteur strain that contains only pXO2. 11 The pXO1 plasmid encodes for 3 components that comprise the 2 exotoxins: edema factor, lethal factor, and PA. Protective antigen, named for the protective immunity it induces against B anthracis infection, combines with either edema factor or lethal factor to form ET or LT, respectively.…”

Zoonoses of dermatologic interest

“…There are two attenuated vaccines available and each carries only one of the plasmids (Pasteur strain carries pXO2 and the Sterne strain carries pXO1) (48). Treatment includes ciprofloxacin or doxycycline.…”