“…Physarum polycephalum Ap 4 A → ADP + ADP Garrison et al, 1982 "Asymmetrical" Nudix Ap 4 A hydrolase Animals (e.g., Nudt2), plants (e.g., AtNUDT25), proteobacteria (RppH/NudH/IalA/YgdP), mycobacteria (MutT1) Guranowski, 2000;McLennan, 2006;Kraszewska, 2008;Arif et al, 2017 Ap 4 A phosphorylase Guranowski and Blanquet, 1985;McLennan et al, 1994McLennan et al, , 1996Hou et al, 2013;Honda et al, 2015 HIT family hydrolases S. cerevisiae (Aph), H. sapiens (FHIT)…”