<i>Aloe vera</i> gel protects liver from oxidative stress-induced damage in experimental rat model

Nahar, Taslima; Uddin, Borhan; Hossain, Shahdat; Sikder, Abdul Mannan; Ahmed, Sohel

doi:10.1515/jcim-2012-0020

Cited by 16 publications

(10 citation statements)

References 21 publications

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“…[76] A. vera gel protects the liver from oxidative stress-induced damage in experimental rat model. [56] Both polysaccharides and phenolic constituents A. vera showed antioxidant and antimycoplasmic activities. [114] Barbaloin and folate showed pharmacological potential.…”

Section: Anti-inflammatorymentioning

confidence: 99%

“…[54] Dried A. vera gel powder reduces body fat mass in diet-induced obesity rats, [55] while its gel protects the liver from oxidative stress-induced damage in experimental rat model. [56] A. vera gel powder is used for colour stability during storage of different packaging materials because of its high shelf-life. [57] For long storage, apple slices are coated with A. vera gel.…”

Section: Nutraceutical Usesmentioning

confidence: 99%

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Upadhyay¹

2018

IJGP

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The present review explains therapeutic and pharmaceutical potential of Aloe vera a well-known plant grows in semi-arid climate of tropical and subtropical regions. This article emphasizes important uses of A. vera constituents as dietary nutraceutical, medicinal, and therapeutic potential. Plant is cultivated for agricultural and medicinal and decoration purposes for indoors as a potted plant. Plant is a good depository of chemical constituents which display a very wide array of biological activities such as anticancer, antiparasitic, antidiabetic, anti-inflammatory, anti-arthritic, antiparasitic, antitumor, antioxidant, chemopreventive, hepatoprotective, and gastroprotective. Plant is used to prepare skin protective/care gels mainly for soothing, moisturizing, and wound healing. Thick watery plant sap works are added as key ingredient in many beauty products. Plant leaves are used to generate aroma, beverages, skin lotion, cosmetics, or ointments for minor burns. Plant contains vitamins, enzymes, minerals, sugars, lignin, saponins, salicylic acids, and amino acids as main ingredients. Plant is a good source of Vitamins A, C, and E, which are antioxidants. It also contains Vitamin B12, folic acid, and choline watery juicy of A. vera leaf which contains important minerals such as calcium, chromium, copper, selenium, magnesium, manganese, and potassium. Plant ingredients were found active against gingivitis, psoriasis, and used for herbal therapy in inflammatory bowel disease. A. vera contains important fatty acids mainly steroids such as cholesterol, campesterol, β-sitosterol, and lupeol. Aloin and emodin act as analgesics, antibacterials, and antivirals while lupeol shows antiseptic and analgesic properties. It also contains auxins and gibberellin hormones that help in wound healing and have anti-inflammatory action. Saponins that are the soapy substances display cleansing and antiseptic properties.

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Section: Anti-inflammatorymentioning

confidence: 99%

Section: Nutraceutical Usesmentioning

confidence: 99%

Untitled

Upadhyay¹

2018

IJGP

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“…Many biological and medicinal properties of Aloe vera are associated with inner gel of the leaves. Several studies have focused on antioxidant effect of Aloe vera (Haritha et al, 2014;Mohamed, 2011;Nahar et al, 2013;Ramachandraiahgari et al, 2012;Trivedi et al, 2015). However, one study showed Aloe vera juice induced oxidative stress and significantly decreased antioxidant enzymes levels (Cock and Sirdaarta, 2011).…”

Section: Araştırma Makalesimentioning

confidence: 99%

“…Several studies have suggested antioxidant effects of Aloe vera (Haritha et al, 2014;Mohamed, 2011;Nahar et al, 2013;Ramachandraiahgari et al, 2012;Trivedi et al, 2015).…”

Section: Trace Elementsmentioning

confidence: 99%

Short Period Starvation in Rat: The Effect of Aloe Vera Gel Extract on Oxidative Stress Status Ion

Mojahed¹,

Saeb²,

Mohammadi³

et al. 2016

İstanbul Üniversitesi Veteriner Fakültesi Dergisi

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The main aim of this experiment was to evaluate the effect of Aloe vera gel extract on oxidative stress status during starvation. For this purpose, twenty-four mature male albino Wistar rats were housed in standard cages. In this study starvation cycle (rats were starved for two days and then were fed for one day) was used. This study was performed during short period (20 days). Animals were divided into four experimental groups (six rats in each group): 1) normal control; 2) starved rats+water/ethanol; 3) starved rats+hydro-alcoholic

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“…Many biological and medicinal properties of Aloe vera are associated with inner gel of the leaves. Several studies have focused on antioxidant effect of Aloe vera [13,14,15,16,17]. However, one study showed Aloe vera juice induced oxidative stress and significantly decreased antioxidant enzymes levels [18].…”

Section: Introductionmentioning

confidence: 99%

Long Period Starvation in Rat: The Effect of Aloe Vera Gel Extract on Oxidative Stress Status

Mojahed

Saeb²,

Mohammadi³

et al. 2016

Int Arch Med

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Objective: Starvation have pro-oxidative effect as a consequence of both elevated ROS generation and defeat in neutralization of ROS. Aloe vera juice induced oxidative stress and significantly decreased antioxidant enzymes levels. The main aim of this experiment was to evaluate the effect of Aloe vera gel extract on oxidative stress status during long period starvation.Method: Twenty-four mature male albino Wistar rats were housed in standard cages. In this study starvation cycle (rats were starved for two days and then were fed for one day) was used. This study was performed during long period (60 days).Animals were divided into four experimental groups (six rats in each group): 1) normal control; 2) starved rats + water/ethanol; 3) starved rats + hydro-alcoholic Aloe vera gel extract (100 mg/kg); 4) starved rats + hydro-alcoholic Aloe vera gel extract (200 mg/kg); 5) Without starvation with hydro-alcoholic Aloe Vera gel extract (100 mg/kg); 6) Without starvation with hydro-alcoholic Aloe Vera gel extract (200 mg/kg). Blood samples were obtained using cardiac puncture. In blood samples, antioxidant enzymes including SOD, GPx and catalase, antioxidant trace elements including copper, zinc and manganese and antioxidant vitamins including vitamin A, vitamin E and vitamin C were measured.

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Aloe vera gel protects liver from oxidative stress-induced damage in experimental rat model

Cited by 16 publications

References 21 publications

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Short Period Starvation in Rat: The Effect of Aloe Vera Gel Extract on Oxidative Stress Status Ion

Long Period Starvation in Rat: The Effect of Aloe Vera Gel Extract on Oxidative Stress Status

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