<i>Aedes aegypti</i> Susceptibility to Insecticide from Abidjan City, Cote D'ivoire

Konan, Lucien Yao; Coulibaly, Ibrahima Zanakoungo; Koné, B; Ziogba, Jean-Claude Tokou; Diallo, Adama; Ekra, D.; Traoré, Karim; Doannio, Marie Christian Julien; Odehouri-Koudou, P.

doi:10.1089/vbz.2011.0617

Cited by 14 publications

(12 citation statements)

References 12 publications

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“…aegypti populations from Dakar during the 2009 dengue outbreak. Our findings are consistent with previous results obtained in Côte d’Ivoire, Cameroon and Burkina Faso [ 21 , 49 , 51 ], although susceptibility to this insecticide is still reported to date in Ae . aegypti in some localities of Congo [ 52 ].…”

Section: Discussionsupporting

confidence: 93%

Insecticide resistance status and mechanisms in Aedes aegypti populations from Senegal

et al. 2021

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Aedes aegypti is the main epidemic vector of arboviruses in Africa. In Senegal, control activities are mainly limited to mitigation of epidemics, with limited information available for Ae. aegypti populations. A better understanding of the current Ae. aegypti susceptibility status to various insecticides and relevant resistance mechanisms involved is needed for the implementation of effective vector control strategies. The present study focuses on the detection of insecticide resistance and reveals the related mechanisms in Ae. aegypti populations from Senegal. Bioassays were performed on Ae. aegypti adults from nine Senegalese localities (Matam, Louga, Barkedji, Ziguinchor, Mbour, Fatick, Dakar, Kédougou and Touba). Mosquitoes were exposed to four classes of insecticides using the standard WHO protocols. Resistance mechanisms were investigated by genotyping for pyrethroid target site resistance mutations (V1016G, V1016I, F1534C and S989P) and measuring gene expression levels of key detoxification genes (CYP6BB2, CYP9J26, CYP9J28, CYP9J32, CYP9M6, CCEae3a and GSTD4). All collected populations were resistant to DDT and carbamates except for the ones in Matam (Northern region). Resistance to permethrin was uniformly detected in mosquitoes from all areas. Except for Barkédji and Touba, all populations were characterized by a susceptibility to 0.75% Permethrin. Susceptibility to type II pyrethroids was detected only in the Southern regions (Kédougou and Ziguinchor). All mosquito populations were susceptible to 5% Malathion, but only Kédougou and Matam mosquitoes were susceptible to 0.8% Malathion. All populations were resistant to 0.05% Pirimiphos-methyl, whereas those from Louga, Mbour and Barkédji, also exhibited resistance to 1% Fenitrothion. None of the known target site pyrethroid resistance mutations was present in the mosquito samples included in the genotyping analysis (performed in > 1500 samples). In contrast, a remarkably high (20-70-fold) overexpression of major detoxification genes wasobserved, suggesting that insecticide resistance is mostly mediated through metabolic mechanisms. These data provide important evidence to support dengue vector control in Senegal.

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Section: Discussionsupporting

confidence: 93%

Insecticide resistance status and mechanisms in Aedes aegypti populations from Senegal

et al. 2021

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“…In sub-Saharan Africa some studies have reported resistance from Ae. aegypti to DDT 4% and pyrethroids with a decrease in susceptibility to carbamates and organophosphates compounds (34, 35, 37, 57).…”

Section: Discussionmentioning

confidence: 99%

“…aegypti populations can limit the success of chemical control. Evidence of this resistance was reported in West Africa (34–37). Many insecticides belonging to pyrethroids, carbamates, and organophosphates are widely used in Burkina Faso for the control of malaria vectors and from which Anopheles gambiae s.l.…”

Section: Introductionmentioning

confidence: 89%

Surveys of Arboviruses Vectors in Four Cities Stretching Along a Railway Transect of Burkina Faso: Risk Transmission and Insecticide Susceptibility Status of Potential Vectors

et al. 2019

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Background: A severe outbreak of dengue occurred in Burkina Faso in 2016, with the most cases reported in Ouagadougou, that highlights the necessity to implement vector surveillance system. This study aims to estimate the risk of arboviruses transmission and the insecticide susceptibility status of potential vectors in four sites in Burkina Faso. Methods: From June to September 2016, house-to-house cross sectional entomological surveys were performed in four cities stretching along a southwest-to-northeast railway transect. The household surveys analyzed the presence of Aedes spp. larvae in containers holding water and the World Health Organization (WHO) larval abundance indices were estimated. WHO tube assays was used to evaluate the insecticide susceptibility within Aedes populations from these localities. Results: A total of 31,378 mosquitoes' larvae were collected from 1,330 containers holding water. Aedes spp. was the most abundant (95.19%) followed by Culex spp. (4.75%). Aedes aegypti a key vector of arboviruses (ARBOV) in West Africa was the major Aedes species found (98.60%). The relative larval indices, house index, container and Breteau indexes were high, up to 70, 35, and 10, respectively. Aedes aegypti tended to breed mainly in discarded tires and terracotta jars. Except in Banfora the western city, Ae. aegypti populations were resistant to deltamethrin 0.05% in the other localities with low mortality rate under 20% in Ouagadougou whereas they were fully susceptible to malathion 5% whatever the site. Intermediate resistance was observed in the four sites with mortality rates varying between 78 and 94% with bendiocarb 0.1%. Conclusions: This study provided basic information on entomological indices that can help to monitor the risks of ARBOV epidemics in the main cities along the railway in Burkina Faso. In these cities, all larval indices exceeded the risk level of ARBOV outbreak. Aedes aegypti the main species collected was resistant to deltamethrin 0.05% and bendiocarb 0.1% whereas they were fully susceptible to malathion 5%. The monitoring of insecticide resistance is also important to be integrated to the vector surveillance system in Burkina Faso.

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“…For example, much of sub-Saharan Africa is predicted to be suitable for Ae . albopictus , but records remain patchy [ 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 ]. Since the worldwide records of each species were compiled, new studies in Africa have reported Ae.…”

Section: Range and Distribution Of Aedes Vectormentioning

confidence: 99%

Aedes Mosquitoes and Aedes-Borne Arboviruses in Africa: Current and Future Threats

Weetman

Kamgang

Badolo

et al. 2018

IJERPH

187

203

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The Zika crisis drew attention to the long-overlooked problem of arboviruses transmitted by Aedes mosquitoes in Africa. Yellow fever, dengue, chikungunya and Zika are poorly controlled in Africa and often go unrecognized. However, to combat these diseases, both in Africa and worldwide, it is crucial that this situation changes. Here, we review available data on the distribution of each disease in Africa, their Aedes vectors, transmission potential, and challenges and opportunities for Aedes control. Data on disease and vector ranges are sparse, and consequently maps of risk are uncertain. Issues such as genetic and ecological diversity, and opportunities for integration with malaria control, are primarily African; others such as ever-increasing urbanization, insecticide resistance and lack of evidence for most control-interventions reflect problems throughout the tropics. We identify key knowledge gaps and future research areas, and in particular, highlight the need to improve knowledge of the distributions of disease and major vectors, insecticide resistance, and to develop specific plans and capacity for arboviral disease surveillance, prevention and outbreak responses.

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Aedes aegypti Susceptibility to Insecticide from Abidjan City, Cote D'ivoire

Cited by 14 publications

References 12 publications

Insecticide resistance status and mechanisms in Aedes aegypti populations from Senegal

Insecticide resistance status and mechanisms in Aedes aegypti populations from Senegal

Surveys of Arboviruses Vectors in Four Cities Stretching Along a Railway Transect of Burkina Faso: Risk Transmission and Insecticide Susceptibility Status of Potential Vectors

Aedes Mosquitoes and Aedes-Borne Arboviruses in Africa: Current and Future Threats

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