AcinetobacterInfections among Adult Patients in Qatar: A 2-Year Hospital-Based Study

Abstract

This retrospective study was conducted at Hamad General Hospital, Qatar, to describe the demographic data, clinical features underlying diseases, antimicrobial susceptibility, and outcome of A. baumannii infection. It involved all adult patients 15 years of age or older who were managed at Hamad General Hospital for A. baumannii infection from January 1, 2012, to December 31, 2013. We identified a total of 239 patients with A. baumannii infection, of which 182 (76.2%) were males. The mean age was 49.10 ± 19.57 years. The majority of the episodes (25.1%) occurred in elderly patients (≥65 years) and the most commonly identified site of A. baumannii infection was the respiratory tract, 117 (48.9%). Most episodes of infection, 231 (96.7%), were hospital-acquired and high rate of nosocomial infections occurred in the medical intensive care unit, 66 (28.6%). All patients had underlying medical conditions. Maximum resistance was seen to cefotaxime, 147 (58.3%), and minimum resistance was seen to colistin, 2 (1.4%). Of the 239 isolates, 102 (42.7%) were susceptible and 137 (57.3%) were multidrug-resistant. The in-hospital mortality in our study was 31%. Male gender, multidrug resistance, and septic shock were found to be independent mortality predictors.

<p>Burden of Multidrug-Resistant <em>Acinetobacter baumannii</em> Infection in Hospitalized Patients in a Tertiary Care Hospital of Nepal</p>

“…15 In our study, MDR A. baumannii was frequently isolated from respiratory tract specimens (47.2%), followed by pus and swabs (27.3%), body fluids (11.1%) and others. A study was done by Shrestha et al in 2015 15 from the same hospital also reported 49.18% of MDR A. baumannii from respiratory tract specimens and Samawi et al 16 from Qatar reported 48.9% A. baumannii from respiratory tract infection. The demographic data in our study showed that a high prevalence of infections in male patients having age ≥65 years and a major of MDR isolates were from ICU patients because this bacteria have a predilection for higher age groups and severly ill ICU patients.…”

Emergence of multidrug-resistant non-fermentative gram negative bacterial infection in hospitalized patients in a tertiary care center of Nepal

“…Acinetobacter species is an important nosocomial pathogen imposing greater problem to the management of hospitalized patients and infection control [18]. Samawi et al [19] from Qatar also reported major A. baumannii from respiratory tract infection. Other Acinetobacter species were commonly isolated from pus and swab samples.…”

Prevalence of antibiotic resistant Escherichia coli isolates from fecal samples of food handlers in Qatar

“…A hospital-based AR bacteria surveillance system exists in Qatar to monitor the incidence of a number of AR bacteria from outpatient and in-patient clinics (Hamad Medical Corporation, Doha, Qatar). However, there is no available information on the AR enteric bacteria such as E. coli from non-clinical samples [ 21 – 23 ].…”