A. caviae infection triggers IL-1β secretion through activating NLRP3 inflammasome mediated by NF-κB signaling pathway partly in a TLR2 dependent manner
Abstract:Aeromonas caviae
, an important food-borne pathogen, induces serious invasive infections and inflammation. The pro-inflammatory IL-1β functions against pathogenic infections and is elevated in various
Aeromonas
infection cases. However, the molecular mechanism of
A. caviae
-mediated IL-1β secretion remains unknown. In this study, mouse macrophages (PMs) were used to establish
A. caviae
infection model and multiple strategies were u… Show more
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