Hystology findings' correlation between the ossicular chain in the transoperative and cholesteatomas

Dornelles, Cristina; Rosito, Letícia Petersen Schmidt; Meurer, Luíse; Costa, Sady Selaimen da; Argenta, Andréia; Alves, Sabrina Lima

doi:10.1016/s1808-8694(15)31169-1

Cited by 21 publications

(17 citation statements)

References 23 publications

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“…There was no evidence of squamous epithelial cells in the ossicles removed from cholesteatomatous cases. Though ossicular necrosis is more in tubotympanic otitis media, several studies [11,12] show variable percentage. Incidence of ossicular involvement of even up to [90% in atticoantral otitis media has been reported [13].…”

Section: Discussionmentioning

confidence: 99%

Middle Ear Cleft in Chronic Otitis Media: A Clinicohistopathological Study

Sharma

Manjari

Salaria

2011

Indian J Otolaryngol Head Neck Surg

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Chronic mucosal diseases of middle ear cleft or chronic suppurative otitis media has been traditionally defined as a chronic inflammation of the middle ear and mastoid usually associated with perforation of the tympanic membrane and otorrhoea. Understanding the pathology and pathogenesis of chronic suppurative otitis media is important in predicting the management, prognosis and sequelae of the disease. The present prospective study was conducted to evaluate the clinical, intraoperative and histopathological changes in middle ear cleft. 100 patients diagnosed with CSOM who underwent surgery were taken. The mucosa and granulation tissue was removed along with ossicles wherever indicated and sent for histopathological examination. On clinical examination, 72 cases were found to be of tubotympanic type and 28 cases of atticoantral variety. However, intraoperatively, of the tubotympanic cases 8 were found to be of unsafe type which was also proven histologically. Stratified squamous epithelium was revealed in most of the cases accompanied by changes in the submucosa. Ossicular chain was involved in 40 cases with incus being the commonest bone to be eroded.

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Section: Discussionmentioning

confidence: 99%

Middle Ear Cleft in Chronic Otitis Media: A Clinicohistopathological Study

Sharma

Manjari

Salaria

2011

Indian J Otolaryngol Head Neck Surg

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“…In their study, Dornelles et al (16) could not find a correlation between patients' age and perimatrix inflammation intensity or granulation tissue thickness and assessed ossicular damage magnitude. Additionally, In our study, no correlation was found between patients' age and reported duration of the disease and ossicular damage magnitude either.…”

Section: Discussionmentioning

confidence: 78%

Comparison of Primary and Secondary Cholesteatomas in Terms of Ossicular Destruction and Complications

Yildirim¹,

Külekçi²,

Sivas³

et al. 2014

Turk Arch Otolaryngol

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“…However, malleus erosion was slightly higher than our study. Dornelles et al [26] (2007), Incus was the most frequently affected and with erosion of long process in 47.6% followed by stapes suprastructure erosion in 32.3% malleus was least eroded.…”

Section: Discussionmentioning

confidence: 96%

Clinico-Pathological Changes in Middle Ear Cleft in Chronic Suppurative Otitis Media

Garg¹,

Palta²,

Verma³

2018

jemds

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BACKGROUND Chronic suppurative otitis media has been traditionally defined as a chronic inflammation of the middle ear and mastoid, usually associated with perforation of the tympanic membrane and otorrhoea. Understanding the pathology and pathogenesis of chronic suppurative otitis media is important in predicting the management, prognosis and sequelae of the disease. MATERIALS AND METHODS The present study was a cross-sectional study that was conducted to evaluate the clinical, intraoperative and histopathological changes in the middle ear cleft. 50 patients diagnosed with CSOM, who underwent surgery were taken. The mucosa and granulation tissue were removed along with ossicles wherever indicated and sent for histopathological examination. RESULTS Incidence of CSOM is highest in 3 rd decade of age with more prevalence in lower socioeconomic group. Females were involved more than males. Unilateral involvement was seen in 64% cases. Otorrhoea and diminished hearing was a constant feature among all cases followed by earache (26%), itching (22%), tinnitus (16%), vertigo (10%) and mass in the ear (6%). On otoscopic examination perforation was seen in 42 cases (84%), while retraction pockets were seen in 8 cases (16%), 7 cases had plastered TM (14%), tympanosclerosis was also found in 6 cases (12%), granulations in 2 cases (4%) and polyp was found in 3 cases (6%). On pure tone audiometry testing, 44 patients (88%) had conductive hearing loss and 6 patients (12%) had mixed hearing loss. CONCLUSION Main conclusion drawn from this study is that on clinical examination 38 cases were found to be of tubotympanic type and 12 cases of atticoantral variety. However, intraoperatively, of the tubotympanic cases, 4 were found to be of unsafe type, which was also proven histologically.

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Hystology findings' correlation between the ossicular chain in the transoperative and cholesteatomas

Abstract: Our findings indicate that ossicular chain changes are practically universal when a cholesteatoma is present. We didn't find correlations related with bone erosion and cholesteatoma's histological findings.

Cited by 21 publications

References 23 publications

Middle Ear Cleft in Chronic Otitis Media: A Clinicohistopathological Study

Middle Ear Cleft in Chronic Otitis Media: A Clinicohistopathological Study

Comparison of Primary and Secondary Cholesteatomas in Terms of Ossicular Destruction and Complications

Clinico-Pathological Changes in Middle Ear Cleft in Chronic Suppurative Otitis Media

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