Hysteroscopy for treating subfertility associated with suspected major uterine cavity abnormalities

Bosteels, Jan; Kasius, Jenneke C.; Weyers, Steven; Broekmans, Frank J.; Mol, Ben Willem J.; D’Hooghe, Thomas

doi:10.1002/14651858.cd009461.pub2

Cited by 55 publications

(38 citation statements)

References 70 publications

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“…These lesions can affect the natural fertility beside affect pregnancy rates [21,22]. Acquired uterine lesions, such as uterine fibroids, endometrial polyps, intrauterine adhesions, or all of these, may cause infertility by interfering with proper embryo implantation and growth [3].…”

Section: Discussionmentioning

confidence: 99%

Uterine Cavity Assessment Prior to ICSI in Patients with Reproductive Failure: 3 Dimensional Gel Instillation Sonohysterography VS. Office Hysteroscopy

Ali¹,

Nasr²,

Ahmed³

et al. 2017

ARC Journal of Gynecology and Obstetrics

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Section: Discussionmentioning

confidence: 99%

Uterine Cavity Assessment Prior to ICSI in Patients with Reproductive Failure: 3 Dimensional Gel Instillation Sonohysterography VS. Office Hysteroscopy

Ali¹,

Nasr²,

Ahmed³

et al. 2017

ARC Journal of Gynecology and Obstetrics

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“…Submucous fibroids interfere with fertility and should be removed in infertile patients, regardless of the size or symptoms [2,26].…”

Section: Discussionmentioning

confidence: 99%

Validity of Hysteroscopy in Detection of Uterine Cavity Abnormalities in Women with Recurrent Pregnancy Loss

M¹

2016

J Gynecol Res Obstet

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Journal of Gynecological Research and Obstetrics 026polyps and adhesion) [5]. Mullerien anomalies have been found in (8-10%) of women with recurrent pregnancy loss and uterine septum was the most common anomaly. Most of the defects are treatable [6]. Rates of conception after hysteroscopic metroplasty in septate uterus, or hysteroscopic cutting of intra-uterine adhesion are stated to be high with 87% conception rate postoperatively [7].In this study, the aim was to evaluate the hysteroscpic value in the management of intrauterine lesion in women with recurrent pregnancy loss. Patients and MethodsThis study was performed in Ain Shams Maternity University Hospital after the approval of the Research Ethics Committee, during the period between Jan 2013 to Jan 2015 where 200 non-pregnant women with a history of three or more consecutive unexplained first and second trimester miscarriages before 20 weeks were recruited from recurrent miscarriage clinic. Written informed consent was taken from all women before participation in this study. Inclusion criteria1. Recurrent abortions (3 times of abortions) or more. No contraindication for hysteroscopy (recent infection).3. Normal progesterone levels in the luteal phase IntroductionRecurrent miscarriage is considered when pregnancy is spontaneously interrupted in three consecutive episodes either before 20 weeks of gestationa or before the fetus is 500g in weight [1]. Recurrent pregnancy loss has major effect on the psycho-social status of couples. It has been demonstrated that up to 3% of women experience recurrent loss of pregnancy and the cause is idiopathic in approximately 50% of cases [2].The etiology of recurrent pregnancy loss can be classified according to their therapeutic potential into potentially treatable and currently untreatable etiologies. The potentially treatable causes are structural defects, endocrine abnormalities (luteal phase defect), thrombotic pregnancies (thrombophilia or autoantibodies) and immunological disorders (immunoglobulins and immunization) the currently untreatable cases are genetic abnormalities and idiopathic etiologies [3].Hysteroscopy offers great help in the interpretation of uncertain findings from other diagnostic modalities. Moreover, it enables direct visualization of cervical canal, uterine cavity and improve the accuracy in the evaluation of intrautrine abnormalities [4]. AbstractObjective: To explore the validity of hysteroscopy in detection of uterine cavity abnormalities in women with recurrent pregnancy loss. Patients and Methods:This was a prospective study performed at Ain Shams University Maternity Hospital, over a 3-year period, between Jan 2013 and Jan 2016, and included 200 women who were presented for evaluation of the cause of repeated early pregnancy loss and scheduled for hysteroscopy for assessment of any uterine cavity abnormality. Participant ages ranged from 18 to 35 years. A written informed consent was obtained from all women before participation.Results: the mean age was 29.5 ± 3.5, the mean number of prev...

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“…Inflammatory cytokines and adhesion molecules that are expressed by the endometrium and embryo are essential for the appropriate interaction between the embryo and the endometrium for successful pregnancy [22,23]. Apolipoprotein A1 has the ability to inhibit the synthesis of inflammatory cytokines and adhesion molecules, such as selections, that have essential roles in the embryo implantation [21,[24][25][26][27]. Another potential mechanism through which apolipoprotein A1 contributes to the implantation failure may be via inhibition of angiogenesis.…”

Section: Discussionmentioning

confidence: 99%

The Expression of Apolipoprotein A1 on Pregnancy Outcome in Women with Polycystic Ovary Syndrome Compared to Fertile Women: A Cross-Sectional Study

Fathy¹

2016

J Gynecol Res Obstet

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Hysteroscopy for treating subfertility associated with suspected major uterine cavity abnormalities

Cited by 55 publications

References 70 publications

Uterine Cavity Assessment Prior to ICSI in Patients with Reproductive Failure: 3 Dimensional Gel Instillation Sonohysterography VS. Office Hysteroscopy

Uterine Cavity Assessment Prior to ICSI in Patients with Reproductive Failure: 3 Dimensional Gel Instillation Sonohysterography VS. Office Hysteroscopy

Validity of Hysteroscopy in Detection of Uterine Cavity Abnormalities in Women with Recurrent Pregnancy Loss

The Expression of Apolipoprotein A1 on Pregnancy Outcome in Women with Polycystic Ovary Syndrome Compared to Fertile Women: A Cross-Sectional Study

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