Hysteroscopic view in atypical endometrial hyperplasias: A correlation with pathologic findings on hysterectomy specimens

Garuti, Giancarlo; Mirra, Maurizio; Luerti, Massimo

doi:10.1016/j.jmig.2006.03.010

Cited by 35 publications

(22 citation statements)

References 23 publications

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“…These results are similar to those in previous reports (Table 5) (Kurman and Norris 1982;Janicek and Rosenshein 1994;Lambert et al 1994;Hunter et al 1994;Liapis et al 1994;Widra et al 1995;Dunton et al 1996;Xie et al 2002;Agostini et al 2002;Kimura et al 2003;Bilgin et al 2004;Shutter and Wright 2005;Merisio et al 2005;Garuti et al 2006;Trimble et al 2006;Dordević et al 2007). Sampling errors Values are shown as a mean (± s.d.…”

Section: Discussionsupporting

confidence: 93%

Hysteroscopic Inspection and Total Curettage Are Insufficient for Discriminating Endometrial Cancer from Atypical Endometrial Hyperplasia

Kurosawa

Itō

Nikura

et al. 2012

Tohoku J. Exp. Med.

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Endometrial cancer (EC) is the most prevalent gynecologic malignancy in Japan. Atypical endometrial hyperplasia (AEH) is viewed as the premalignant lesion of EC, however it is often difficult to distinguish EC from AEH. The rate of concurrent EC in women diagnosed preoperatively with AEH based on endometrial biopsy was reported as 17-52%. Although hysteroscopic inspection and total curettage are considered as useful methods to make diagnosis of endometrial lesions, there is no report using this combined method to discriminate EC from AEH. The purpose of this study was to examine whether hysteroscopic inspection and total curettage improve the prevalence of EC among women diagnosed preoperatively with AEH. We reviewed 22 patients who underwent hysteroscopic inspection and total curettage and were diagnosed with AEH before undergoing hysterectomy between November 2001 and May 2011. The diagnosis made with the hysterectomy specimens revealed AEH in 10 patients (45.5%), endometrial hyperplasia without atypia in 3 (13.6%), and endometrioid adenocarcinoma, the most common type of EC, in 9 (40.9%). Endometrioid adenocarcinoma included 7 patients without myometrial invasion (31.8%) and 2 patients with superficial myometrial invasion (9.1%). There was no hysteroscopic finding that was specific for EC or AEH. In conclusion, about 41% of women who underwent hysterectomy under a diagnosis of AEH were found to have coexisting adenocarcinoma, although the prevalence of EC among those women was similar to that in earlier reports with endometrial biopsy. Accordingly, we must be careful in planning the therapeutic strategy for women with a preoperative diagnosis of AEH.

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Section: Discussionsupporting

confidence: 93%

Hysteroscopic Inspection and Total Curettage Are Insufficient for Discriminating Endometrial Cancer from Atypical Endometrial Hyperplasia

Kurosawa

Itō

Nikura

et al. 2012

Tohoku J. Exp. Med.

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show abstract

“…27 In another study rewieving the hysteroscopic reports of 25 menopausal patients treated by hysterectomy, the correlation was found between the pathologic findings on the uterine specimen and the diagnoses obtained by hysteroscopic view. 28 Also, sensitivity, specificity, and negative and positive predictive values of hysteroscopy to foresee a diagnosis of infiltrating carcinoma were 84.6%, 100%, 87.5%, and 100%, respectively in patients with a diagnosis of atypical hyperplasia on endometrial biopsy.…”

Section: Discussion and Literature Reviewmentioning

confidence: 89%

Endometrial Sampling Methods: A Case Report and Literature Review

Aksoy¹,

Aksoy²,

Kurt³

et al. 2015

Turkiye Klinikleri J Gynecol Obst

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“…Every recording systematically visualized the anterior wall, the fundus, the ostia, sidewalls, and posterior wall and covered the whole uterine cavity. Evaluation of video clips was performed according to defined standard criteria based on morphologic evaluation of the endometrium [30,43] and recorded on a standard form. The endometrial pattern was evaluated systematically by each observer with regard to localized or diffuse lesions, surface structure, necrosis, and vascular pattern.…”

Section: Patientsmentioning

confidence: 99%

Reproducibility of Endometrial Pathologic Findings Obtained on Hysteroscopy, Transvaginal Sonography, and Gel Infusion Sonography in Women With Postmenopausal Bleeding

Dueholm

Hjorth

Secher

et al. 2015

Journal of Minimally Invasive Gynecology

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Hysteroscopic view in atypical endometrial hyperplasias: A correlation with pathologic findings on hysterectomy specimens

Cited by 35 publications

References 23 publications

Hysteroscopic Inspection and Total Curettage Are Insufficient for Discriminating Endometrial Cancer from Atypical Endometrial Hyperplasia

Hysteroscopic Inspection and Total Curettage Are Insufficient for Discriminating Endometrial Cancer from Atypical Endometrial Hyperplasia

Endometrial Sampling Methods: A Case Report and Literature Review

Reproducibility of Endometrial Pathologic Findings Obtained on Hysteroscopy, Transvaginal Sonography, and Gel Infusion Sonography in Women With Postmenopausal Bleeding

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