Hysteroscopic removal of retained products of conception: historic approach or new iteration?

Verma, Usha; Crespo, Frank A.

doi:10.21037/atm-2020-119

Cited by 2 publications

(2 citation statements)

References 7 publications

(6 reference statements)

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“…While antibiotics are not primarily indicated for miscarriage prevention, they are often administered when surgical procedures are necessitated to remove uterine tissue following pregnancy loss ( Verma and Crespo, 2020 ). Infection following miscarriage can have long-term effects such as pelvic scarring, a rise in ectopic pregnancy rates, and infertility ( Melese et al., 2017 ).…”

Section: Microbiota Based Interventional Strategies To Prevent and Tr...mentioning

confidence: 99%

Role of the vaginal microbiome in miscarriage: exploring the relationship

Saadaoui,

Singh,

Ortashi

et al. 2023

Front. Cell. Infect. Microbiol.

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Miscarriage is a devastating pregnancy loss that affects many women worldwide. It is characterized as a spontaneous miscarriage that occurs before 20 weeks of gestation which affects more than 25% of pregnancies. While the causes of miscarriage are complex and multifactorial, recent research has suggested a potential role of the vaginal microbiota. The vaginal microbiome is a dynamic ecosystem of microbes that are essential for preserving vaginal health and avoiding infections. Vaginal dysbiosis has been accompanied with numerous adverse pregnancy complications, such as preterm birth. However, the effect of the vaginal microbiome in miscarriage is not fully understood. This review aims to investigate the link between vaginal microbiota and miscarriage. Also, we investigate the various mechanisms through which the vaginal microbiota may affect miscarriage. Additionally, we examine the implications of these research findings, specifically the possibility of vaginal microbiome screening and targeted interventions to prevent miscarriage.

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Section: Microbiota Based Interventional Strategies To Prevent and Tr...mentioning

confidence: 99%

Role of the vaginal microbiome in miscarriage: exploring the relationship

Saadaoui,

Singh,

Ortashi

et al. 2023

Front. Cell. Infect. Microbiol.

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“…However, the appropriate management of RPOC remains unknown because its natural course is unclear [10]. The ability to predict RPOC with severe PPH is particularly important because it guides management strategies that range from conservative treatment to invasive surgery [11][12][13][14].…”

Section: Introductionmentioning

confidence: 99%

Clinical Prediction of Retained Products of Conception: Combining Obstetric History and Ultrasound for Improved Accuracy in Severe Postpartum Hemorrhage

Kurakazu,

Kiyoshima

et al. 2024

Cureus

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Background The current challenge is how to improve the management of postpartum hemorrhage (PPH) to reduce the maternal mortality rate further. This study aimed to investigate whether a combined specific obstetric history and ultrasonographic findings can improve the predictive accuracy of retained products of conception (RPOC) with severe PPH. Methods This retrospective study included 56 patients who were diagnosed with RPOC. We extracted the following clinical data: obstetric history of second-trimester miscarriage, the time at which there was clinical suspicion of RPOC after the previous pregnancy (TIME), grayscale ultrasonographic finding (RPOC long-axis length [SIZE]), and color Doppler ultrasonographic finding based on the Gutenberg classification (RPOC hypervascularity). In this study, we defined cases requiring blood transfusion therapy or transcatheter arterial embolization as severe PPH. The patients were divided into two groups according to the presence or absence of severe PPH. The predictors of severe PPH were evaluated using logistic regression models. Model A comprised a combination of second-trimester miscarriage and TIME, Model B comprised a combination of Model A and long-axis SIZE, and Model C comprised a combination of Model B and RPOC hypervascularity. Results The multivariable analysis showed that long-axis SIZE was the only significant predictor of severe PPH (odds ratio [OR], 10.38; 95% confidence interval [CI], 2.06-63.86) independent of second-trimester miscarriage, TIME, and RPOC hypervascularity. The c-statistic was higher in Model C (OR, 0.863; 95% CI, 0.731-0.936) than in Model A (OR, 0.723; 95% CI, 0.551-0.847) and Model B (OR, 0.834; 95% CI, 0.677-0.923). Conclusion Combining a specific obstetric history (second-trimester miscarriage and TIME) and ultrasonographic findings (long-axis SIZE and RPOC hypervascularity) improves the predictive accuracy of RPOC with severe PPH. This prediction model may be a useful clinical screening tool for RPOC with severe PPH.

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Hysteroscopic removal of retained products of conception: historic approach or new iteration?

Cited by 2 publications

References 7 publications

Role of the vaginal microbiome in miscarriage: exploring the relationship

Role of the vaginal microbiome in miscarriage: exploring the relationship

Clinical Prediction of Retained Products of Conception: Combining Obstetric History and Ultrasound for Improved Accuracy in Severe Postpartum Hemorrhage

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