Hysterectomized women with ovarian conservation report more severe climacteric complaints than do normal climacteric women of similar age

Oldenhave, A.; Jaszmann, L; Everaerd, Walter; Haspels, A.A.

doi:10.1016/s0002-9378(12)90816-9

Cited by 142 publications

(60 citation statements)

References 24 publications

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“…In a cross-sectional survey involving 986 hysterectomized women with one or both ovaries preserved and 5636 non-hysterectomized women with both ovaries, far fewer of the non-hysterectomized reported worsening of migraine compared to the hysterectomized group (8.8 vs. 15.1 %, respectively) [26]. This finding contrasts with previous observations and appears to emphasize only the importance of the presence or absence of the uterus.…”

Section: Migraine and Surgical Menopausecontrasting

confidence: 60%

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Migraine in perimenopausal women

et al. 2015

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Hormonal changes during the reproductive cycle are thought to account for the variation in migraine occurrence and intensity. Although the majority of women and the specialists treating them do not consider migraine as a component of the climacteric syndrome, many women, in fact, do experience migraine during perimenopause. If a woman already suffers from migraine, the attacks often worsen during menopausal transition. Initial onset of the condition during this period is relatively rare. Women with the premenstrual syndrome (PMS) prior to entering menopause are more likely to experience, during late menopausal transition, an increased prevalence of migraine attacks. Hormone replacement therapy (HRT) can be initiated during the late premenopausal phase and the first years of postmenopause to relieve climacteric symptoms. The effect of HRT on migraine, either as a secondary effect of the therapy or as a preventive measure against perimenopausal migraine, has been variously investigated. HRT preparations should be administered continuously, without intervals, to prevent sudden estrogen deprivation and the migraine attacks that will ensue. Wide varieties of formulations, both systemic and topical, are available. Treatment with transdermal patches and estradiol-based gels is preferable to oral formulations as they maintain constant blood hormone levels. Natural menopause is associated with a lower incidence of migraine as compared with surgical menopause; data on the role of hysterectomy alone or associated with ovariectomy in changing the occurrence of migraine are till now unclear.

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Section: Migraine and Surgical Menopausecontrasting

confidence: 60%

“…Natural menopause is associated with a lower incidence of migraine as compared with surgical menopause [4,26,27]. The difference was present also when these two groups of women were compared, considering only those with PMS [8].…”

Section: Migraine and Surgical Menopausementioning

confidence: 96%

Migraine in perimenopausal women

et al. 2015

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“…In addition, it is possible that hysterectomy without bilateral oophorectomy causes vaginal dryness by hastening ovarian failure. Oldenhave et al 16 found that compared with women whose uteri are intact, women with prior hysterectomy and no bilateral oophorectomy were more likely to have vaginal dryness.…”

Section: Vaginal Drynessmentioning

confidence: 99%

Hysterectomy and Sexual Functioning

Rhodes

Kjerulff²,

Langenberg

1999

JAMA

266

173

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“…A função ovariana pós-histerectomia é um assunto muito controverso na literatura e na prá-tica médica diária. Muitos pesquisadores descreveram modificações na função ovariana após a histerectomia, por alterações no aporte sangüíneo gonadal, podendo levar à menopausa mais precoce e conseqüentemente a uma perda mais acentuada da massa óssea [5][6][7][8][9] . Sendo a osteoporose e as fraturas as principais conseqü-ências tardias da falência ovariana, realizamos este estudo, que teve como objetivo principal avaliar as alterações na massa óssea em mulheres histerectomizadas menopausadas, quando comparadas às não-histerectomizadas.…”

Section: Resultados: As Médias Etárias íNdice De Massa Corporal Corunclassified