Hypoxic training to improve exercise capacity in obesity: a randomized controlled trial

Vergès, Samuel; Chacaroun, Samarmar; Borowik, Anna; Gonzalez, Ignacio Vega-Escamilla Y; Doutreleau, Stéphane; Wuyam, Bernard; Belaidi, Élise; Tamisier, Renaud; Pépin, Jean‐Louis; Flore, Patrice

doi:10.1183/13993003.congress-2020.1929

Cited by 2 publications

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“…Hypoxic training has become a popular approach in the sports community, attracting the attention of both athletes and researchers seeking effective methods to improve performance at sea level [9]. The combination between physical training and hypoxia exposure has also been proposed as a new therapeutic strategy aiming to improve the overall health in overweight and obese individuals [10]. The increasing prevalence of obesity and its coexisting diseases not only imposes a significant health burden, but also carries significant economic consequences, creating serious challenges for healthcare systems and generating treatment costs [6].…”

Section: Introductionmentioning

confidence: 99%

The Impact of Intermittent Hypoxic Training on Aerobic Capacity and Biometric-Structural Indicators among Obese Women—A Pilot Study

Bagińska,

Kałuża,

Tota

et al. 2024

JCM

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Background: Obesity, a common lifestyle-related condition, is correlated with factors like inadequate physical activity. Its connection to diverse health issues presents a significant challenge to healthcare. This pilot study investigated the effects of hypoxic training on aerobic capacity and biometric-structural indicators in obese women. The secondary objective was to determine the feasibility, effectiveness, and safety of the planned research procedures and their potential for larger-scale implementation. Material and methods: Forty-one non-trained women with first-degree obesity were randomly assigned to even normobaric hypoxic training (H + E), normoxic training (E), passive exposure to hypoxia (H), and a control group (C). Training sessions were conducted three times a week for four weeks (12 training sessions). Body composition parameters were assessed, metabolic thresholds were determined, and maximal oxygen consumption (VO2max) was measured before and after interventions. Results: The results demonstrated that training in hypoxic conditions significantly affected somatic parameters, with the H + E group achieving the best outcomes in terms of weight reduction and improvements in body composition indicators (p < 0.001). Normoxic training also induced a positive impact on body weight and body composition, although the results were less significant compared to the H + E group (p < 0.001). Additionally, training in hypoxic conditions significantly improved the aerobic capacity among the participants (p < 0.001). The H + E group achieved the best results in enhancing respiratory endurance and oxygen consumption (p < 0.001). Conclusions: The results of this pilot study suggest, that hypoxic training can be effective for weight reduction and improving the aerobic capacity in obese women. Despite study limitations, these findings indicate that hypoxic training could be an innovative approach to address obesity and related conditions. Caution is advised in interpreting the results, considering both the strengths and limitations of the pilot study. Before proceeding to a larger-scale study, the main study should be expanded, including aspects such as dietary control, monitoring physical activity, and biochemical blood analysis.

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Section: Introductionmentioning

confidence: 99%

The Impact of Intermittent Hypoxic Training on Aerobic Capacity and Biometric-Structural Indicators among Obese Women—A Pilot Study

Bagińska,

Kałuża,

Tota

et al. 2024

JCM

View full text Add to dashboard Cite

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“…Meanwhile, some researchers explore the effect of multimodel interventions such as a combination of physical exercise and antioxidative supplement intake. For example, a systematic review and meta-analysis concluded that vitamins C and E could be used to prevent oxidative stress, but could not enhance performance or improve muscle mass (Dutra et al, 2020), another randomized, double-blind, crossover study found that coenzyme Q10 supplementation could partially prevent the increase in lipid peroxidation after repeated shortterm supramaximal exercise (Gül et al, 2011), a three-armed trial showed that regular physical activities and massage manipulations could significantly increase SOD activities (Karabulut et al, 2013), and a randomized controlled trial claimed that a combination of exercise training and hypoxic exposure could improve oxidation status of obese individuals (Verges et al, 2020). Similarly, because of the difference in intervention protocols, differences in measures, and the fact that some trials study acute effects and others long-term effects, it is difficult to synthesize the evidence.…”

Section: Introductionmentioning

confidence: 99%

Effect of Physical Exercise Under Different Intensity and Antioxidative Supplementation for Plasma Superoxide Dismutase in Healthy Adults: Systematic Review and Network Meta-Analysis

Liang

Ugbolue

et al. 2022

Front. Physiol.

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BackgroundThe dynamic balance between oxidation and anti-oxidation in the body’s internal environment has a significant meaning for human health. Physical exercise and antioxidative supplementation could affect the balance of oxidation and anti-oxidation systems. The evidence on the effects of physical exercise and antioxidative supplementation is mixed.AimsTo identify the effects of physical exercise, antioxidative supplementation, and their combination on the dynamic balance between oxidation and anti-oxidation in different subgroups of healthy adults.MethodsAll studies which reported randomized controlled trials with healthy participants were screened and included from the databases of PubMed, Medline, Embase, and Ovid. All participants were reclassified according to their different daily life activities. All physical exercise interventions were reclassified according to the intensity. The effect size would be calculated in percent or factor units from the mean level change with its associated random-effect variance.ResultThere were 27 studies included in this review. The agreement between authors by using The Cochrane Collaboration Risk of Bias Assessment Tool reached a kappa-value of 0.72. Maintaining a regular physical exercise routine in an appropriate intensity would be beneficial to the body’s anti-oxidative potential. Anti-oxidative supplementation could have some positive but limited effects on the body’s anti-oxidative status and complex interaction with physical exercise.ConclusionKeeping a regular physical exercise routine and gradually increasing its intensity according to the individual’s daily life activity might be a better choice to maintain and enhancing the body’s antioxidation potential, only using anti-oxidative supplementation is not recommended. More research is needed to explore the best combination protocol.Registration NumberCRD42021241995.

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Hypoxic training to improve exercise capacity in obesity: a randomized controlled trial

Cited by 2 publications

References 0 publications

The Impact of Intermittent Hypoxic Training on Aerobic Capacity and Biometric-Structural Indicators among Obese Women—A Pilot Study

The Impact of Intermittent Hypoxic Training on Aerobic Capacity and Biometric-Structural Indicators among Obese Women—A Pilot Study

Effect of Physical Exercise Under Different Intensity and Antioxidative Supplementation for Plasma Superoxide Dismutase in Healthy Adults: Systematic Review and Network Meta-Analysis

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