Hypoxic training: Clinical benefits on cardiometabolic risk factors

Wee, Justin; Climstein, Mike

doi:10.1016/j.jsams.2013.10.247

Cited by 40 publications

(35 citation statements)

References 45 publications

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“…4 However, the eff ects of hypoxic training vary greatly according to the oxygen concentration, exercise intensity, time and duration, and among individuals. However, there is disagreement regarding the eff ects of exercise in a hypoxic environment on lipid metabolism, with some studies reporting no change and others reporting improvements in markers.…”

Section: Resultsmentioning

confidence: 99%

“…The improvements in body composition and reduction in body weight associated with hypoxic training may correlate with the increased basal metabolic rate observed under hypoxic conditions. 4 An increased metabolic rate may result from improved substrate utilization and mitochondrial oxidation, 15 via signalling pathways that stimulate GLUT-4 transport. 4,16 Hypoxic conditions are also associated with increased leptin production, 17,18 which can suppress appetite and hence improve body composition.…”

Section: Discussionmentioning

confidence: 99%

“…4 An increased metabolic rate may result from improved substrate utilization and mitochondrial oxidation, 15 via signalling pathways that stimulate GLUT-4 transport. 4,16 Hypoxic conditions are also associated with increased leptin production, 17,18 which can suppress appetite and hence improve body composition. 16 A previous study involving hypoxic training (O 2 , 15%) for middle-aged obese subjects over 4 weeks indicated that the reduction in body fat content with training was greater in the hypoxic group than in the normoxic group.…”

Section: Discussionmentioning

confidence: 99%

“…4,16 Hypoxic conditions are also associated with increased leptin production, 17,18 which can suppress appetite and hence improve body composition. 16 A previous study involving hypoxic training (O 2 , 15%) for middle-aged obese subjects over 4 weeks indicated that the reduction in body fat content with training was greater in the hypoxic group than in the normoxic group. 18,19 In this study, the weight, BMI, body fat percentage and waist circumference were reduced after hypoxic training, regardless of physique, supporting the results of previous studies.…”

Section: Discussionmentioning

confidence: 99%

“…3 Our fi nding that hypoxic training did not increase LDL levels is consistent with the fi ndings of a number of previous studies; however, our HDL results are inconsistent. 4 Wee and Climstein found that hypoxic training signifi cantly reduced total cholesterol (TC) levels in obese subjects with dyslipidemia and metabolic syndrome. 4 However, the extent of the reduction beyond the eff ects of exercise has varied, and there have been few controlled studies.…”

Section: F1 = Difference Between Groups; F2 = Difference Before and Amentioning

confidence: 99%

See 4 more Smart Citations

Influences of Short-Term Normobaric Hypoxic Training on Metabolic Syndrome-Related Markers in Overweight and Normal-Weight Men

Shin

Matsuoka

2018

J Men's Health

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: F1 = Difference Between Groups; F2 = Difference Before and Amentioning

confidence: 99%

See 3 more Smart Citations

Influences of Short-Term Normobaric Hypoxic Training on Metabolic Syndrome-Related Markers in Overweight and Normal-Weight Men

Shin

Matsuoka

2018

J Men's Health

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Body fat attenuates muscle mass catabolism among physically active humans in temperate and cold high altitude environments

Ocobock

2017

American J Hum Biol

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Adaptations following an intermittent hypoxia‐hyperoxia training in coronary artery disease patients: a controlled study

Глазачев

Kopylov

Суста

et al. 2017

Clinical Cardiology

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Background Repeated exposure to intermittent normobaric hypoxia improves exercise tolerance in cardiac patients. Little is known on the effects of intermittent normobaric hypoxia‐hyperoxia exposure in coronary artery disease (CAD) patients (New York Heart Association II–III). Hypothesis IHHT improves exercise tolerance, cardiometabolic profile, and quality of life in CAD patients. Methods The study design was a nonrandomized, controlled, before‐and‐after trial. Forty‐six CAD patients volunteered to take part in the study: a group of 27 patients undertook the intermittent hypoxia (O2 at 10%)–hyperoxia (O2 at 30%) training (IHHT), whereas a control group (CTRL) of 19 patients, who already completed an 8‐week standard cardiac rehabilitation program, was allocated to sham‐IHHT treatment (breathing room air, O2 at 21%). Exercise performance, blood and metabolic profiles, and quality of life (Seattle Angina Questionnaire [SAQ]) were measured before and after in the IHHT group (IHHG) and sham‐IHHT in the CTRL group. Results The IHHG showed improved exercise capacity, reduced systolic and diastolic blood pressures, enhanced left ventricle ejection fraction, and reduced glycemia, but only at 1‐month follow‐up. Angina as a reason to stop exercising was significantly reduced after treatment and at 1‐month follow‐up. The IHHT SAQ profile was improved in the IHHG and not significantly different to the CTRL group after standard rehabilitation. The IHHG was also compared to the CTRL group at 1‐month follow‐up, and no differences were found. Conclusions In CAD patients, an IHHT program is associated with improved exercise tolerance, healthier risks factors profile, and a better quality of life. Our study also suggests that IHHT is as effective as an 8‐week standard rehabilitation program.

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Hypoxic training: Clinical benefits on cardiometabolic risk factors

Cited by 40 publications

References 45 publications

Influences of Short-Term Normobaric Hypoxic Training on Metabolic Syndrome-Related Markers in Overweight and Normal-Weight Men

Influences of Short-Term Normobaric Hypoxic Training on Metabolic Syndrome-Related Markers in Overweight and Normal-Weight Men

Body fat attenuates muscle mass catabolism among physically active humans in temperate and cold high altitude environments

Adaptations following an intermittent hypoxia‐hyperoxia training in coronary artery disease patients: a controlled study

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