“…We read with great interest the paper by Mestry et al 1 which analysed hypoxic challenge flight assessments in patients with restrictive disorders. In their study they dispute the current British Thoracic Society recommendations, demonstrating that, in this subgroup, all patients planning air travel should have a pre-flight evaluation because, even in patients with normal baseline oxygen saturation (Sa o 2 ), arterial oxygen tension (Pa o 2 ) can fall below 6.6 kPa during hypoxic challenge.…”