Abstract:Fetal neural stem cells (FNSCs) present in the human fetal brain, differentiate into cells of neuronal and glial lineages. The developing fetus is exposed to lower oxygen concentrations compared to adults and this physiological hypoxia may influence the growth and differentiation of the FNSCs. This study aimed to evaluate the effect of hypoxia on the differentiation potential of human FNSCs isolated from the sub-ventricular zone of aborted fetal brains (n = 5). FNSCs were isolated, expanded, and characterized … Show more
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