Hypoxia-Induced Insulin Resistance Mediates the Elevated Cardiovascular Risk in Patients with Obstructive Sleep Apnea: A Comprehensive Review
María M. Adeva-Andany,
Alberto Domínguez-Montero,
Elvira Castro-Quintela
et al.
Abstract:Patients with obstructive sleep apnea (OSA) experience insulin resistance and
its clinical consequences, including hypertriglyceridemia, reduced high density
lipoprotein-associated cholesterol (HDL-c), visceral adiposity, hepatic
steatosis, increased epicardial fat thickness, essential hypertension, glucose
intolerance, increased risk for type 2 diabetes, chronic kidney disease,
subclinical vascular damage, and increased risk for cardiovascular events.
Obesity is a major contributor to OSA. The prevalenc… Show more
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