Hypovitaminosis D in Obese and Overweight Schoolchildren

Çizmecioğlu, Filiz Mine; Etiler, Nilay; Görmüş, Uzay; Hamzaoğlu, Onur; Hatun, Şükrü

doi:10.4008/jcrpe.v1i2.43

Cited by 38 publications

(44 citation statements)

References 33 publications

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“…In the literature, some reports showed no interaction of BMI and 25(OH)D, but particularly studies on adults and a few on children and adolescents demonstrated a relationship between obesity status and serum 25(OH)D (15,26,62) . In the study by Ç izmecioglu et al in obese and overweight adolescents with hypovitaminosis D, serum 25(OH)D level decreased as BMI increased (6) . It is believed that extra body fat, by sequestration of 25(OH)D, may reduce its bioavailability (63) .…”

Section: Discussionmentioning

confidence: 99%

“…Recent studies suggest that vitamin D deficiency is no longer just a problem of the older generations but also is an important health concern among younger generations (4) . Studies in the last two decades have shown a high prevalence of vitamin D deficiency in healthy adolescents in different countries (5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15) . In Iran, Razzaghy-Azar and Shakiba and Moussavi et al reported that 67 % of female children and adolescents in Tehran and 72?1 % of teenage girls in Isfahan had vitamin D deficiency, with higher rates of deficiency in girls than boys (16,17) .…”

Section: Vitamin D Prevalence Metabolic Syndrome Adolescent Girlsmentioning

confidence: 99%

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Vitamin D status and its relationship with metabolic syndrome risk factors among adolescent girls in Boukan, Iran

Rafraf

Hasanabad

Jafarabadi

2013

Public Health Nutr.

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Objective: To investigate vitamin D status and its association with components of the metabolic syndrome (MetS) in adolescent girls attending high school in Boukan, Iran during winter 2012. Design: A cross-sectional study. Setting: High schools of Boukan city, Iran. Subjects: A sample of 216 girls aged 14-17 years was selected by multistage random sampling from four districts of Boukan. Weight, height, waist circumference, blood pressure, daily energy intake, physical activity and serum 25-hydroxyvitamin D (25(OH)D), fasting blood glucose, TAG and HDL-cholesterol levels of all participants were evaluated. Serum 25(OH)D level ,20 ng/ml was defined as vitamin D deficiency. Results: Mean serum 25(OH)D was 7?26 (SD 2?81) ng/ml and 96 % of the participants had vitamin D deficiency. According to age-modified definitions of the National Cholesterol Education Program Adult Treatment Panel III, MetS was diagnosed in 10?6 % of the participants. In multivariable regression analysis after adjustment for BMI, energy intake and physical activity level, serum 25(OH)D was inversely associated with fasting blood glucose (b 5 20?143, P 5 0?04). No significant relationship was found between serum 25(OH)D and other components of MetS. Conclusions: The high prevalence of vitamin D deficiency warrants national polices and interventions towards improving this major health problem among adolescent girls. Low 25(OH)D level was significantly associated with increased fasting blood glucose. Prospective studies are needed to determine the effects of vitamin D deficiency on the development of MetS and related metabolic diseases in adolescent girls. Keywords Vitamin D Prevalence Metabolic syndrome Adolescent girlsVitamin D deficiency is a major public health problem and an unrecognizable condition of epidemic proportions in both developed and developing countries, with widespread reports of 30-93 % prevalence in children and adults (1)(2)(3) . Determination of vitamin D status in different age groups in a community and in different climates of a country is necessary and has important implications for general health. Recent studies suggest that vitamin D deficiency is no longer just a problem of the older generations but also is an important health concern among younger generations (4) . Studies in the last two decades have shown a high prevalence of vitamin D deficiency in healthy adolescents in different countries (5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15) . In Iran, Razzaghy-Azar and Shakiba and Moussavi et al. reported that 67 % of female children and adolescents in Tehran and 72?1 % of teenage girls in Isfahan had vitamin D deficiency, with higher rates of deficiency in girls than boys (16,17) . Vitamin D is known as the 'sunshine vitamin' because the mean exposure to sunlight should be sufficient for most people to produce their own vitamin D using UV light and cholesterol in the skin (18) . Whenever sun exposure is insufficient, dietary intake of this vitamin becomes a necessity. However, there are few dietary sources of vitamin D...

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Section: Discussionmentioning

confidence: 99%

Section: Vitamin D Prevalence Metabolic Syndrome Adolescent Girlsmentioning

confidence: 99%

Vitamin D status and its relationship with metabolic syndrome risk factors among adolescent girls in Boukan, Iran

Rafraf

Hasanabad

Jafarabadi

2013

Public Health Nutr.

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“…30 In Turkey, hypovitaminosis D rate was 59.4-65.0 %. 31,32 Low levels of Vit D has been implicated in various diseases, including neoplastic, inflammatory, demyelinating, cardiovascular and diabetic ones. Some authors has focused on association between levels of Vit D and MS and found that low serum Vit D concentrations were associated with the development of MS. [33][34][35] In our study we compared Vit D levels in individulas with and without MS. Vit D concentrations were statistically lower in our patients with MS than individuals without MS.…”

Section: Resultsmentioning

confidence: 99%

Relationship Between Levels of Vitamin D and Metabolic Syndrome Parameters in Patients with Metabolic Syndrome and Healthy Individuals

Evrim¹,

Atalay²,

Gürsoy³

et al. 2016

Turkiye Klinikleri J Endocrin

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A AB BS S TTR RA AC CT T O Ob bj je ec ct ti iv ve e: : Hypovitaminosis D and metabolic syndrome are worldwide common problems. The link between them was unresolved. We planned to define the relation between Vitamin D levels and metabolic syndrome and also their parameters. M Ma at te er ri ia al l a an nd d M Me et th ho od ds s: : We evaluated all the demographic and anthropometric parameters of 79 healthy participants and 95 patients with metabolic syndrome and compared those parameters and vitamin D levels. We classified 25(OH)D serum levels; <10ng/mL as serious deficiency, 10-20 ng/mL as deficiency, 20-30 ng/mL insufficiency and > 30 ng/mL as normal status. We searched the correlation of vitamin D levels with metabolic syndrome parameters. We also examined the relation of various Vitamin D levels with demographic and anthropometric findings of metabolic syndrome patients. R Re es su ul lt ts s: : Vitamin D levels were low in all the individuals (12.8 ± 6.7ng/mL in patients and 19.0 ± 10.0ng/mL in controls. p<0.001). In metabolic syndrome patients, serious deficiency was high and normal Vit D status was significantly low especially in females. In metabolic syndrome group vitamin D levels were negatively correlated with body mass index, waist circumference, blood glucose, hemoglobin A1c, fasting insulin, insulin resistance index (p <0.012, <0.040, <0.002, <0.008, <0.006, <0.001 respectively). We found that vitamin D levels of the patients without hypertension, diabetes mellitus, dyslipidemia or obesity were higher than that of the patients with those diseases among metabolic syndrome group (all p<0.001). We also demonstrated as Vitamin D levels decreased, rate of obesity, hypertension and diabetes mellitus increased, (p<.0.029, <0.035 and <0.001 respectively). C Co on nc cl lu us si io on n: : In patients with metabolic syndrome hypovitaminosis D is frequent especially in women. As Vitamin D levels are in negative correlation with obesity, diabetes and insulin resistance indices and also with metabolic syndrome parameters, we concluded that Vitamin D supplementation is important in hypovitaminosis D cases with metabolic syndrome. Ya zış ma Ad re si/Cor res pon den ce:

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“…[23] Various reports from different countries have shown that vitamin D is commonly associated with obesity in children. [24] Findings of the current study have shown that vitamin D was significantly low in obese children compare to control children.…”

Section: Discussionmentioning

confidence: 99%

Vitamin D and its Relation with Insulin Resistance in Obese Children

Mathur¹,

Soni²,

Kukreja³

2018

AIMDR

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Background: Deficiency of vitamin D leads to mal skeletal growth in children; moreover it is becoming an epidemic throughout the world. Decrease level of vitamin D can cause diverse of skeletal disorders in children like rickets, osteopenia etc. The relationship of vitamin D, obesity and insulin resistance is still not clear in the literature. Vitamin D deficiency may induce the altered glucose tolerance in obese children. Therefore the present study was designed to investigate the relationship of vitamin D and insulin resistance in obese children. Methods: The present study was a cross sectional type of study which was conducted in paediatric department of TMMC & RC, Moradabad. This study included 120 obese children (60 males and 60 females) of mean age 12 ± 2.6 years in group I. Control group II contained 100 healthy none obese children (50 males and 50 females) of 12.2 ± 1.8 years. Insulin resistance was calculated from fasting plasma measurements using HOMA-IR (insulin (mU/L) × glucose (mmol/l)/22.5). Insulin resistance criteria were HOMA-IR >2.5 for children. Vitamin D was measured by ELISA method (kit manufactured by Cayman chemical company, Ann Arbor, USA). Results: There was an insignificant difference in the FBG (>0.05) of group I obese children and group II control. Insulin (<0.05) and HOMA-IR (<0.01) were significantly low in obese children in comparison of none-obese children. Vitamin D (<0.01) was significantly lower in obese children compare to healthy children. vitamin D was negatively correlated with BMI (r = -0.42, r2 =0.1764, p<0.05) in obese children. There was a negative correlation between vitamin D and insulin resistance (r = -0.52, r2 =0.2704, p<0.05) in obese children. Conclusion: Present study suggests that there was strong relation between insulin resistance and obesity. Vitamin D was negatively correlated with BMI and insulin resistance. These findings strongly suggest vitamin D level may found insufficient or deficient in obese children. Therefore, obese children should be screened for vitamin D deficiency for their normal skeletal growth.

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Hypovitaminosis D in Obese and Overweight Schoolchildren

Cited by 38 publications

References 33 publications

Vitamin D status and its relationship with metabolic syndrome risk factors among adolescent girls in Boukan, Iran

Vitamin D status and its relationship with metabolic syndrome risk factors among adolescent girls in Boukan, Iran

Relationship Between Levels of Vitamin D and Metabolic Syndrome Parameters in Patients with Metabolic Syndrome and Healthy Individuals

Vitamin D and its Relation with Insulin Resistance in Obese Children

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