Hypovitaminosis D and Other Risk Factors of Femoral Neck Fracture in South Indian Postmenopausal Women: A Pilot Study

Paul, Thomas; Selvan, Saravanan; Asha, Hesarghatta Shyamasunder; Nicolaï, Thomas; Krishnan, Venkatesh; Oommen, Anil Thomas; Mathai, Thomas; Seshadri, MandalamSubramanian

doi:10.7860/jcdr/2015/9444.6131

Cited by 20 publications

(29 citation statements)

References 29 publications

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“…A study from Poland observed this among 85% of elderly patients without fractures [24]. A few indian studies among hip fracture patients found the prevalence of vitamin d deficiency (taken as < 20 ng/mL) ranging between 74% to 76.7% [11,15], similar to our study finding (75.5%, at < 20 ng/mL). A study from South india among patients presenting with an orthopaedic trauma also found hypovitaminosis at a level of 95% [10].…”

Section: Discussionsupporting

confidence: 90%

“…This may be attributed to the fact that in old age, the skin and gut are less efficient in producing and absorbing vitamin d, respectively, while immobility among this population decrease the chances of going outdoors and exposure to sunlight [5]. Studies assessing the role of vitamin d as a cause of fractures among the elderly and in the general population is lacking in india, barring a handful of studies among postmenopausal women [15]. Given the importance of vitamin d in overall wellbeing, as well as for musculoskeletal strength, data enlightening the prevalence of vitamin d deficiency in elderly patients could be of great value for policy makers and family physicians.…”

Section: Introductionmentioning

confidence: 99%

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Assessment of Vitamin D deficiency among older adult patients with an orthopaedic fracture and its association with increasing age

2019

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Background. orthopaedic fractures are one of the common presentations among elderly patients at any primary care facility. While most researches have labelled osteoporosis as being responsible for these fractures in the elderly, vitamin d deficiency, despite being prevalent in all races, age groups and ethnic backgrounds, is given lesser importance. Objectives. To assess vitamin d level and its relation with advancing age among older adults presenting with an orthopedic fracture. Material and methods. A cross-sectional study was performed at one of the orthopaedic oPd, in tertiary care hospital from North india. The patients 45 years and above presenting with orthopaedic fracture were eligible and out of whom 102 were included in the study. For assessing vitamin d level, we measured serum 25(oH)d level, taking cutoff for deficiency, insufficiency and normal levels at < 10, 10-29 and 30 ng/ml or more respectively. Results. out of 102 elderly patients we selected, 59% were male and 41% were females, with the mean age of 61 ± 13.4 years. Majority of them (94.2%) had low serum vitamin d levels. We observed lower levels of vitamin d level to be significantly associated with higher age, menopausal females and no sunlight exposure. Conclusions. With almost all older patients with fracture had low vitamin d levels and its high association with advancing age, we recommend to screen all people for vitamin d deficiency, starting middle age and proper management to prevent fracture in elderly.

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Section: Discussionsupporting

confidence: 90%

Section: Introductionmentioning

confidence: 99%

Assessment of Vitamin D deficiency among older adult patients with an orthopaedic fracture and its association with increasing age

2019

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“…Low serum vitamin D status and serum calcium further aggravates osteoporosis because of chronic secondary Hyperparathyroidism associated bone resorption, a problem well documented in Indian population. 15 Overall prevalence of osteoporosis among postmenopausal women were found to be 54% and 49% according to measured bone mineral density at distal radius and calcaneum respectively. Other studies had also reported high prevalence of osteoporosis in their studies.…”

Section: Discussionmentioning

confidence: 92%

“…Results were comparable with other studies. 6,15 However a study conducted by Kataria et al 21 reported no correlation between BMD and BMI. Overweight may protect postmenopausal women against bone loss.…”

Section: Body Mass Index (Bmi) and Bone Mineral Density (Bmd)mentioning

confidence: 98%

Vitamin D Levels and Its Relationship With Bone Mineral Density Among Postmenopausal Women in Central India

Godara¹

2017

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BACKGROUND To determine vitamin D (25OHD) status and its relationship with bone mineral density (BMD) in 100 postmenopausal women. MATERIALS AND METHODS Postmenopausal women were included according to inclusion and exclusion criteria and serum 25OHD and a peripheral DXA scan of the forearm (distal radius) and calcaneum were taken. RESULTS Mean±SD of serum 25OHD levels were 18.0±8.07 ng/ml. The prevalence of vitamin D deficiency was 62%. Patients with hypovitaminosis D had a lower BMD at the distal radius and at calcaneum (p<0.05%). CONCLUSION We found a high prevalence of hypovitaminosis D and osteoporosis in postmenopausal women. Age, body mass index and vitamin D levels were correlated with bone mineral density at both sites (i.e. at distal radius and at calcaneum).

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“…One of the common causes of hypothyroidism is Hashimoto's thyroiditis. [1][2][3] In women, the risk of developing hypothyroidism increases with age and during pregnancy, the postpartum period, and menopause. Iodine deficiency is the most common cause of hypothyroidism worldwide.…”

Section: Introductionmentioning

confidence: 99%

Importance of Tubercle of Zuckerkandl in Thyroid Surgery

Kc¹,

Panda²,

Minz³

et al. 2016

IJMRP

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Background: Hypothyroidism, a disease in which the thyroid gland does not make enough thyroid hormone, is the second most common endocrine disorder among women. It is important to obtain appropriate diagnostic tests to facilitate prompt diagnosis and treatment. A health history is useful to evaluate for symptoms of hypothyroidism, past treatment for hyperthyroidism, use of drugs that influence thyroid hormones, or a history of iodine deficiency. Hence; we planned the present study to assess thyroid deficient among females visiting the OPD of MMG District Hospital, Ghaziabad, Uttar Pradesh. Materials & Methods:The present study included assessment of patients attending the hospital OPD with thyroid hormone deficiencies. A total of 50 patients were included in the present study. Fresh blood samples were obtained from all the patients and Thyroid-stimulating hormone (TSH) assay was done. Complete demographic details of all the patients were recorded. We also analyzed the clinical signs and symptoms present in all the patients. All the results were recorded on Microsoft excel sheet and were analyzed by SPSS software. Results: Majority of the patients were above 50 years of age with 19 patients more than 60 years of age. We observed significant results while comparing the number of patients divided on the basis of age group and gender. We also observed significant results while evaluating the presence of type I diabetes and family history as risk factors for development of thyroid hormone deficiency. Conclusion: Thyroid hormone deficiencies disproportionately affect women and elderly patients in higher proportion.

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Hypovitaminosis D and Other Risk Factors of Femoral Neck Fracture in South Indian Postmenopausal Women: A Pilot Study

Cited by 20 publications

References 29 publications

Assessment of Vitamin D deficiency among older adult patients with an orthopaedic fracture and its association with increasing age

Assessment of Vitamin D deficiency among older adult patients with an orthopaedic fracture and its association with increasing age

Vitamin D Levels and Its Relationship With Bone Mineral Density Among Postmenopausal Women in Central India

Importance of Tubercle of Zuckerkandl in Thyroid Surgery

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