Hypothyroidism Manifesting as a Combination of Ascites and Malnutrition Requiring Total Parenteral Nutrition: A Unique Presentation

Zafar, Yousaf; Suddaby, S.; Shafiq, Muhammad

doi:10.7759/cureus.5338

Cited by 3 publications

(1 citation statement)

References 13 publications

(14 reference statements)

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“…These values are similar to our study, although only individuals with DS and hypothyroidism were included. However, several studies reported no decrease in the z-score of the nutritional status as a result of hypothyroidism 28 . The hypothyroid condition is a hypometabolic state in which the basal metabolic rate (BMR) decreases 29,30 , hence, some individuals with hypothyroidism experience excess nutrients rather than a lack 31 .…”

Section: Resultsmentioning

confidence: 99%

Height-for-age in Children under 5 Years Old with Down Syndrome and Hypothyroidism

Muhammad Faizi,

Nur Rochmah,

Yuni Hisbiyah

et al. 2021

Indian Journal of Forensic Medicine & Toxicology

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Background:Children with Down syndrome tend to have accompanying comorbidities, such as hypothyroidism, and late detection of this ailment leads to reduced growth of the child. This study aimed to assess the growth patterns in children with Down Syndrome and hypothyroidism at diagnosis. Methods:This cross-sectional study was conducted from September to December 2020 with 56 subjects at the Pediatric Endocrine Outpatient Clinic of Dr. Soetomo Hospital. Diagnosis of Down Syndrome was confirmed by karyotyping, while the weights and heights were assessed using a standardized curve for children with Down Syndrome and then calculated using Peditools. Fifty-six children with Down Syndrome and hypothyroidism were included, comprising 32 boys and 24 girls (mean age, 37.75 ± 34.26 months). Majority of the subjects had normal weight, height, and Body Mass Index (36/56 [mean z-score, −1.62 ± 2.36], 33/56 [mean height-z-score, −0.43 ± 2.74], and 30/56 [mean z-score, −2.00 ± 2.06], respectively). Furthermore, the mean onset of diagnosis was 17.07 ± 32.23 months, where 23 out of the 56 children had short stature and had gotten diagnosed at over 12 months of age. Conclusion:From the results obtained, hypothyroidism can be said to be associated with reduced growth in children with DS.

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Section: Resultsmentioning

confidence: 99%

Height-for-age in Children under 5 Years Old with Down Syndrome and Hypothyroidism

Muhammad Faizi,

Nur Rochmah,

Yuni Hisbiyah

et al. 2021

Indian Journal of Forensic Medicine & Toxicology

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Hypothyroidism and Transudative Ascites: Highlighting a Little-known Association

Barry,

Diack,

Ndiaye

et al. 2024

IJDE

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Hypothyroidism is a frequent condition in medical practice and clinical forms with ascites are exceptionally rare. After a review of the literature we found that the exudative nature of the fluid is the main feature associated with hypothyroidism, however no case of hypothyroidism associated with transudative ascites has been reported. We report a case of transudative ascites associated with hypothyroidism in a post thyroidectomy setting. This 72-year-old patient underwent total thyroidectomy 3 years ago, without supplementation with synthetic thyroid hormone. He had been treated in cardiology for compensated ischaemic heart disease for 4 months. He presented with apathy, significant physical asthenia and a hoarse voice. His general condition was altered, with a rounded, puffy face and infiltrated eyelids. The feet were oedematous. Haemodynamic constants revealed arterial hypotension. Ascites aspiration yielded a sterile, pauci-cellular, citrine-yellow, transudative fluid. After ruling out renal, glomerular and hepatic causes, the ascites persisted despite optimised treatment of his heart disease, making cardiac ascites unlikely. Signs of hypometabolism and myxedema, together with a very high TSH (TSHus = 54.26 microgr/L) and disappearance of ascites after thyroid hormone supplementation, supported the hypothesis of transudative ascites associated with hypothyroidism. Ascites associated with hypothyroidism is rare and the transudative nature of the fluid is exceptional; it is generally included in myxedema. Hypothyroidism is rarely manifested by ascites but can be considered after ruling out common causes. Hormonal treatment allows complete regression of ascites within a few weeks and constitutes a therapeutic test.

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Ascites, Pleural, and Pericardial Effusion in Primary Hypothyroidism: A Rare Case Report

Gomes Santos,

Calças Marques,

Martins dos Santos

et al. 2023

Cureus

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Hypothyroidism Manifesting as a Combination of Ascites and Malnutrition Requiring Total Parenteral Nutrition: A Unique Presentation

Cited by 3 publications

References 13 publications

Height-for-age in Children under 5 Years Old with Down Syndrome and Hypothyroidism

Height-for-age in Children under 5 Years Old with Down Syndrome and Hypothyroidism

Hypothyroidism and Transudative Ascites: Highlighting a Little-known Association

Ascites, Pleural, and Pericardial Effusion in Primary Hypothyroidism: A Rare Case Report

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