Hypothyroïdie du sujet âgé

Acute Hepatitis-Like Syndrome Revealing Hashimoto Thyroiditis

“…Major acute hepatocellular necrosis remains an uncommon presentation of hypothyroidism: a single patient in Bensalem W et al series of 70 cases of hypothyroidism of the elderly (1.4%) [10] and to our knowledge only two cases of acute hepatitis-like syndrome revealing hypothyroidism have been reported previously in the world literature [11][12] our observation is thus the third reporting this mode of revelation.…”

“…Disturbances in hepatic biologic tests are not uncommon during hypothyroidism, but classically refer to rhabdomyolysis [9]. More rarely, moderate chronic cholestasis and, exceptionally, isolated hypertransamenaemia can be observed which are reversible [9][10]. Pseudo-acute hepatitis syndrome (acute hepatitis-like syndrome) remains an unusual presentation of this autoimmune endocrinopathy [11][12].…”