Hypothalamic Obesity and Wasting Syndromes

Uwaifo, Gabriel I.

doi:10.1007/978-3-030-62187-2_12

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2023

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“…The neuroendocrine neurons release various neurotransmitters and/ or neuropeptides, such as neuropeptide Y (NPY), agouti-related peptide (AgRP), cocaine-and amphetamine-regulated transcript (CART), dopamine, gonadotropin-releasing hormone (GnRH), growth hormone-releasing hormone (GHRH), kisspeptin (Kiss1), neurokinin B (NKB), dynorphin A, proopiomelanocortin (POMC) and substance P (SP). The centrally-projecting neurons transmit information to other hypothalamic nuclei or other brain regions outside the hypothalamus [2,[5][6][7].…”

Section: Introductionmentioning

confidence: 99%

Arcuate Nucleus of the Hypothalamus: Anatomy, Physiology, and Diseases

Song,

Choi

2023

Exp Neurobiol

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The hypothalamus is part of the diencephalon and has several nuclei, one of which is the arcuate nucleus. The arcuate nucleus of hypothalamus (ARH) consists of neuroendocrine neurons and centrally-projecting neurons. The ARH is the center where the homeostasis of nutrition/metabolism and reproduction are maintained. As such, dysfunction of the ARH can lead to disorders of nutrition/metabolism and reproduction. Here, we review various types of neurons in the ARH and several genetic disorders caused by mutations in the ARH.

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Section: Introductionmentioning

confidence: 99%