2024
DOI: 10.3390/ani14030513
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Hypothalamic Neuromodulation of Hypothermia in Domestic Animals

Daniel Mota-Rojas,
Marcelo Daniel Ghezzi,
Ismael Hernández-Ávalos
et al.

Abstract: When an organism detects decreases in their core body temperature, the hypothalamus, the main thermoregulatory center, triggers compensatory responses. These responses include vasomotor changes to prevent heat loss and physiological mechanisms (e.g., shivering and non-shivering thermogenesis) for heat production. Both types of changes require the participation of peripheral thermoreceptors, afferent signaling to the spinal cord and hypothalamus, and efferent pathways to motor and/or sympathetic neurons. The pr… Show more

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“…After tissue damage, proinflammatory mediators are released, causing the vasodilation of capillaries, venules, or arterioles, with a subsequent increase in local temperature [ 13 , 14 , 15 ]. On the other hand, local hypothermia can be seen in patients with vascular compromise and ischemia issues [ 16 , 17 ].…”
Section: Introductionmentioning
confidence: 99%
“…After tissue damage, proinflammatory mediators are released, causing the vasodilation of capillaries, venules, or arterioles, with a subsequent increase in local temperature [ 13 , 14 , 15 ]. On the other hand, local hypothermia can be seen in patients with vascular compromise and ischemia issues [ 16 , 17 ].…”
Section: Introductionmentioning
confidence: 99%