Hypotension Begins at 110 mm Hg: Redefining “Hypotension” With Data

Abstract

Taking the BD and mortality measurements together, this analysis shows that a SBP < or =110 mm Hg is a more clinically relevant definition of hypotension and hypoperfusion than is 90 mm Hg. This analysis will also be useful for developing appropriately powered studies of hemorrhagic shock.

A Predictive Model for Massive Transfusion in Combat Casualty Patients

“…Recently, in a study reviewing the National Trauma Data Bank, Eastridge et al identified the blood pressure at admission associated with increased mortality to be approximately 110 mm Hg, far above the standard reference for shock of 90 mm Hg. 40 Studies such as the Eastridge study, the Yücel study (which assigns significant point values for SBP below 120 mm Hg and greater still for SBP less than 100 mm Hg) and our study continue to demonstrate increased morbidity and mortality at SBPs much higher than previously considered indicative of "hypotension" or shock.…”

Effect of Plasma and Red Blood Cell Transfusions on Survival in Patients With Combat Related Traumatic Injuries

“…We chose to define shock as a base deficit of Ն4 because the normal range of base deficit is Ϫ3 to ϩ3 and recent evidence published in a study of over 800,000 trauma patients that mortality starts to increase at a base deficit above 4. 40 Base deficit of Ն4 was also chosen for the cut off point in our regression analysis as a result of it being the value that was most accurate with predicting death by receiver operating curve analysis.…”

Erratum to: Shock in the emergency department; a 12 year population based cohort study

“…We chose to use a higher threshold (100 mmHg) of hypotension than the traditional 90 mmHg. This decision was based on increasing evidence advocating for a redefinition of arterial hypotension [8][9][10][11], which we also have underlined in a recent study within our research unit [12]. The primary date of contact defined the index date.…”