Hyposplenism, Hashimoto's Autoimmune Thyroiditis and Overlap Syndrome (Celiac Disease and Autoimmune Hepatitis Type 1)

Bălăceanu, Alice; Omer, Secil; Stirban, Raluca; Zara, Octavian; Dina, Ion

doi:10.1016/j.amjms.2020.04.022

Cited by 5 publications

(5 citation statements)

References 57 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Splenic hypofunction is unrelated to the period of a gluten-free diet ( 35 , 36 ). This relationship is significant because hyposplenic individuals are at higher risk of developing catastrophic inflammation caused by gram-negative bacteria (e.g., capnocytophaga canimorsus) as well as encapsulated bacteria (e.g., Streptococcus pneumonia, Neisseria meningitides , and Haemophilus influenza type b) ( 37 , 38 ). In a survey conducted among general practitioners in Pakistan, their level of understanding regarding the differentiation between celiac disease and irritable bowel syndrome was investigated.…”

Section: Discussionmentioning

confidence: 99%

Potential determinants of vaccine hesitancy among celiac disease patients: a single cohort analysis

Rehman

Holy

2023

Front. Public Health

View full text Add to dashboard Cite

IntroductionThough researchers and scholars have greatly emphasized addressing the influencing factors of vaccination hesitancy, little attention has been paid to patients with celiac disease. Addressing the variables hampering attitudes might help direct appropriate patient advocacy and doctor-patient communication endeavors to encourage vaccination among celiac disease patients. The present investigation seeks to explore the coverage against vaccine-preventable diseases, vaccination attitudes, and related possible factors among celiac disease patients in the Pakistani setting.MethodsA self-reported online survey was conducted in Islamabad, Pakistan, for celiac disease patients aged 18 and above. The questionnaire was completed by 226 participants, with a response rate of 43.8%. The influencing variables for vaccination hesitancy were examined, and 95% confidence intervals for the crude and adjusted odds ratios were computed.ResultsAmong the study population, the majority were females, with a ratio of 75.66%. A prominent proportion of 69.03% was observed for influenza vaccination, while 39.82% were unable to recall all of the vaccinations they had previously received. Only 7% of the patients were considered to have a negative attitude toward vaccination, compared to an estimated 76% who were in favor of it. The significantly positive influencing factors observed toward vaccination were being well-educated (graduate, master, or above), possible recurrence of vaccine-preventable diseases with declining vaccination coverage (adjusted OR: 13.36), and increased confidence in vaccines from health care experts compared to electronic media (adjusted OR: 8.41). Contrarily, practicing complementary and alternative medicines (adjusted OR: 5.59), willingness to get vaccinated again in the future (adjusted OR: 15.59), and prior negative perspectives (adjusted OR: 1.01) were the determinants with a significant negative association.DiscussionIn conclusion, the outcomes of the current work raise the possibility that health practitioners may be accountable for inappropriately prescribing vaccines to this demographic since 77% of the participants had a favorable attitude toward vaccination. These findings could serve as a springboard for creating targeted immunization efforts to raise vaccination coverage against vaccine-preventive diseases among celiac disease patients.

show abstract

Section: Discussionmentioning

confidence: 99%

Potential determinants of vaccine hesitancy among celiac disease patients: a single cohort analysis

Rehman

Holy

2023

Front. Public Health

View full text Add to dashboard Cite

show abstract

“…In some studies, the authors confirm that patients with AH are more likely to develop concomitant autoimmune disease of the thyroid gland. Patients who had AITD and AILD showed higher levels of IgG, since IgG was positively correlated with thyroid antibodies and thyroperoxidase antibodies 13,14 16 .…”

Section: Archives Of Public Healthmentioning

confidence: 96%

Autoimmune Hashimoto thyroiditis with concomitant autoimmune hepatitis

Manevska

Stojkovska²,

Tasheva³

et al. 2022

Arch Pub Health

View full text Add to dashboard Cite

So far, the literature data have presented a combination of several autoimmune triggered disease in patients, but the research is scarce and very limited. In this context we present a rare case of autoimmune thyroiditis with a concomitant autoimmune hepatitis. Hashimoto thyroiditis is an autoimmune disorder in which immune cells lead to impairment, destruction of the thyroid hormone producing cells and tissue fibrosis with consecutive primary hypothyroidism. Autoimmune hepatitis is a chronic liver disease with unknown etiology, which is assumed to be T cell mediated condition where immune cells produce autoantibodies responsible for inflammation, destruction and fibrosis of the hepatic parenchyma. In this case report, we discuss the possible correlation in the spectrum of autoimmune diseases concerning Hashimoto thyroiditis and autoimmune hepatitis.

show abstract

“…When the symptomatic form is present, the most characteristic symptoms include gastrointestinal disorders, malabsorption, weight loss and developmental delay in children [12,13]. Serological tests, i.e.…”

Section: Dietmentioning

confidence: 99%

“…Coeliac disease can be diagnosed either before or after the diagnosis of autoimmune disease [10]. Both diseases are HLA-coupled [11,13]. The prevalence of CD in patients with autoimmune thyroid disease is increasing [10,12].…”

Section: Dietmentioning

confidence: 99%

Hashimoto's disease - the role of factors and diet in the course of the disease

Gąbka,

Dalmata,

Gendek

et al. 2023

J Educ Health Sport

View full text Add to dashboard Cite

Introduction: Hashimoto's disease is an autoimmune disorder that develops as a result of a pathological reaction of the patient's immune system, which consequently destroys the body's own healthy cells and tissues. Genetic, environmental and immunological factors influence its development. The disease may initially be asymptomatic. The exact aetiology of the disease is unknown. The worldwide incidence is approximately 10-12%. Purpose: This paper aims to present the influence of genetic factors, environmental factors, trace elements, and diet on the development and course of Hashimoto's disease based on the current state of knowledge. Conclusions: Hashimoto's disease is a multifactorial disease, but the relevance of all factors presented in the development and progression has not yet been confirmed. To date, a special diet for patients has not been created. Further research is needed to better understand the pathogenesis of the disease in order to help patients control HT. Methods: Data for the article were retrieved using PubMed setting the time descriptors to 2013-2023.

show abstract

Hyposplenism, Hashimoto's Autoimmune Thyroiditis and Overlap Syndrome (Celiac Disease and Autoimmune Hepatitis Type 1)

Cited by 5 publications

References 57 publications

Potential determinants of vaccine hesitancy among celiac disease patients: a single cohort analysis

Potential determinants of vaccine hesitancy among celiac disease patients: a single cohort analysis

Autoimmune Hashimoto thyroiditis with concomitant autoimmune hepatitis

Hashimoto's disease - the role of factors and diet in the course of the disease

Contact Info

Product

Resources

About