Hypoplastic Left Heart Syndrome

Bardo, Dianna M. E.; Frankel, David G.; Applegate, Kimberly E.; Murphy, Daniel J.; Saneto, Russel P.

doi:10.1148/radiographics.21.3.g01ma09705

Cited by 55 publications

(35 citation statements)

References 20 publications

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“…1,2 Palliative reconstructive surgery has become the preferred treatment option, although cardiac transplantation may offer better long-term survival. 3 Palliative reconstructive surgery is performed over 3 stages.…”

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confidence: 99%

Cardiac Magnetic Resonance Imaging After Stage I Norwood Operation for Hypoplastic Left Heart Syndrome

Muthurangu

Taylor²,

Hegde³

et al. 2005

Circulation

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Background-After the Norwood operation, a patient's suitability for proceeding to a bidirectional cavopulmonary connection (BCPC) is assessed by a combination of echocardiography and diagnostic cardiac catheterization. In this study, we describe the results of 37 patients who underwent cardiovascular magnetic resonance (MR) assessment before BCPC. Methods and Results-Cardiovascular MR and echocardiography were performed in 37 infants with hypoplastic left heart syndrome before BCPC, and the findings were compared with surgical findings. MR assessment of ventricular function and valvar regurgitation were compared with echocardiography. MR exhibited high sensitivity and specificity for identification of neoaortic (sensitivity 86%, specificity 97%) and left pulmonary artery (sensitivity 100%, specificity 94%) obstruction. Echocardiography exhibited poor sensitivity for identification of vascular stenosis. The mean right ventricular ejection fraction calculated from the MR data was 50Ϯ10%.

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confidence: 99%

Cardiac Magnetic Resonance Imaging After Stage I Norwood Operation for Hypoplastic Left Heart Syndrome

Muthurangu

Taylor²,

Hegde³

et al. 2005

Circulation

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“…20 It implemented on a graft for children suffering of an underdeveloped heart that have undergone a Fontan procedure. 21,22 The pump can be as simple as a gelatin coated graft enliven by a pincher. Gelatin coated graft are already available, and one would only need to engineer one with a thicker gelatin layer to produce a "graft-pump."…”

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confidence: 99%

Resonant pumping in a multilayer impedance pump

2008

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This paper introduces the concept of multilayer impedance pump, a novel pumping mechanism inspired by the embryonic heart structure. The pump is a composite two-layer fluid-filled elastic tube featuring a thick gelatinous internal. Pumping is based on the impedance pumping mechanism. In an impedance pump, elastic waves are generated upon external periodic compressions of the elastic tube. These waves propagate along the tube's walls, reflect at the tube's extremities, and drive the flow in a preferential direction. The originality in the multilayer impedance pump design relies on the use of the thick internal gelatinous layer to amplify the elastic waves responsible for the pumping. As a consequence, only small excitations are needed to produce significant flow. This fully coupled fluid-structure interaction problem is solved for the flow and the structure using the finite element method over a relevant range of frequencies of excitation. Results show that the multilayer impedance pump is a complex system that exhibits a resonant response. Flow output and inner wall motion are maximal when the pump is actuated at the resonant frequency. The wave interaction mechanism present in an impedance pump is described here in details for the case of a multilayer impedance pump. Using energy balance for the passive portion of the elastic tube, we show that the elastic tube itself works as a pump and that at resonance maximum energy transmission between the elastic tube and the fluid occurs. Finally, the pump is especially suitable for many biomedical applications.

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“…It is seen with a hypoplastic mitral valve, and rarely with mitral atresia and a hypoplastic left ventricle or rudimentary left ventricle without a left atrioventricular connection. If the mitral valve is patent, the size of the ventricles may be different (4,5). In our case, the diameter of the ascending aorta was 1mm and it was ligamentous in appearance.…”

Section: Discussionmentioning

confidence: 61%

Fetal cardiac circulation in isolated aortic atresia assessed with ultrasound

Sayit

İpek

Kurt³

et al. 2012

J Turkish German Gynecol Assoc

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Congenital heart diseases are common, with an incidence of more than 8 in 1000 live births. Aortic atresia is a rare diagnosis and its prognosis is very poor. In this article, we present a case of isolated aortic atresia, a very rare cardiovascular anomaly, and its fetal ultrasound findings which include blood flow at foramen ovale from left to right, right deviation of the interventricular septum, dysfunction of the mitral valve and cardiomegaly. Aortic stenosis should be considered in the differential diagnosis of aortic atresia. However, in the case of severe aortic stenosis and/or accompanying ventricular septal defect, differential diagnosis may not be done.

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Hypoplastic Left Heart Syndrome

Cited by 55 publications

References 20 publications

Cardiac Magnetic Resonance Imaging After Stage I Norwood Operation for Hypoplastic Left Heart Syndrome

Cardiac Magnetic Resonance Imaging After Stage I Norwood Operation for Hypoplastic Left Heart Syndrome

Resonant pumping in a multilayer impedance pump

Fetal cardiac circulation in isolated aortic atresia assessed with ultrasound

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