Hypophosphatemic Rickets secondary to Fanconi Syndrome and Hypogonadotropic Hypogonadism; A Rare Case Report and Literature Review

Abstract

A 14-year-old female patient presented with generalized body weakness and difficulty walking. Further history revealed growth and pubertal delay. On examination there was wrist widening, bowing of legs with breast, and pubic hair of tanner stage 2. Serum and urine investigations presented diagnoses of Fanconi syndrome associated with hypophosphatemic rickets with low LH and FSH levels and normal prolactin. MRI showed a normal-sized pituitary gland without any mass lesion. The patient was started with phosphorus, magnesium, and calcium supplements with 25(OH)D.