Hypoparathyroidism, Brain Calcifications and Seizures

Abstract

Background: The most common cause of hypoparathyroidism is iatrogenic in the context of surgical procedures to the neck and commonly the thyroid gland. Hypoparathyroidism is characterized by hypocalcaemia, hyperphosphatemia and low or inappropriately normal levels of parathyroid hormone (PTH) and may be associated with multiorgan complications and variable clinical presentation. Seizures may be the only presenting symptom and may result in antiepileptic therapy. Knowledge of all possible consequences of hypoparathyroidism is essential for correct patient management.