Hyponatremia of Hypothyroidism

Macaron, Chamel; Famuyiwa, Olufunsho

doi:10.1001/archinte.1978.03630290100035

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Cited by 34 publications

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“…Amongthe various hypotheses which have been proposed to explain the hyponatremia in hypothyroidism, inappropriate secretion of ADH (2,3,8) and adreno-cortical dysfunction (4, 9) have been frequently described. However, changes in the glomerular filtration rate, renal plasma flow and tubular excretory capacity (5, 6) have also been observed in hypothyroidism and are potential causes of hyponatremia.…”

Section: Discussionmentioning

confidence: 99%

Hyponatremia with Increased Plasma Antidiuretic Hormone in a Case of Hypothyroidism.

et al. 2000

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Wereport a 70-year-old womanwith hypothyroidism and severe hyponatremia. Her plasma antidiuretic hormone (ADH) level was inappropriately high for her low plasma osmolality. Her low serum sodium level was gradually corrected by water restriction and sodium supplementation prior to the initiation of thyroid hormone replacement. After a diagnosis of Hashimoto's thyroiditis had been made, the patient was treated with levothyroxine. Following this treatment, the patient's serum sodium level increased drastically. It is suggested that the elevated plasma ADHlevel played an important role in the development of hyponatremia in this case.

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Section: Discussionmentioning

confidence: 99%