Hyponatremia Associated With Bupropion, a Case Verified by Rechallenge

Bagley, Steven C.; Yaeger, Deborah

doi:10.1097/01.jcp.0000150232.91995.22

Cited by 22 publications

(16 citation statements)

References 3 publications

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“…However, hyponatremia is not rare condition following a treatment with SSRI and antipsychotic drugs1-5). Case reports of hyponatremia associated with SSRI began appearing in 1989.…”

Section: Discussionmentioning

confidence: 99%

“…Estimates of hyponatremia associated with SSRI and SNRI use vary from 0.5-32%. Curiously, there are only few case reports published regarding bupropion induced hyponatremia1,2). Some experts have suspected the mechanism that serotonin plays a role in regulating the secretion and release of alcoholdehydrogenase (ADH)7-9).…”

Section: Discussionmentioning

confidence: 99%

“…The drug is a non-tricyclic antidepressant and its primary pharmacological action is to inhibit norepinephrine-dopamine reuptake. Although bupropion does not act as TCA and SSRI, there are few case reports describing how bupropion is associated with hyponatremia1,2). We present a case of bupropion induced hyponatremia for the first time in the Korea.…”

Section: Introductionmentioning

confidence: 91%

“…Antidepressants, including the selective serotonin reuptake inhibitor (SSRI) and the tricyclic antidepressants (TCA) often cause hyponatremia1-5). Bupropion is an atypical antidepressant and smoking cessation aid.…”

Section: Introductionmentioning

confidence: 99%

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Hyponatremia Associated with Bupropion

Kim

Choi

Bae

et al. 2011

Electrolyte Blood Press

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Bupropion is widely used for the treatment of depressive disorder and smoking cessation. Hyponatremia, including a syndrome of inappropriate secretion of antidiuretic hormone (SIADH), is not rare complication of treatment with antipsychotic drugs. We report a 60-year-old man who experienced severe hyponatremia after a treatment with bupropion for depressive disorder for the first time in the Korea.

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“…However, hyponatremia is not rare condition following a treatment with SSRI and antipsychotic drugs1-5). Case reports of hyponatremia associated with SSRI began appearing in 1989.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 91%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Hyponatremia Associated with Bupropion

Kim

Choi

Bae

et al. 2011

Electrolyte Blood Press

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“…Hyponatremia can occur with SSRIs, SNRIs, and mirtazapine. Although at least two published case reports attribute hyponatremia to bupropion, other factors that may have been responsible for the hyponatremia also were present [61,62].…”

Section: Hyponatremiamentioning

confidence: 93%

Medically serious adverse effects of newer antidepressants

Mago

Mahajan²,

Thase³

2008

Curr Psychiatry Rep

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Although safer than tricyclic antidepressants and monoamine oxidase inhibitors, the newer antidepressants may be associated with certain medically serious adverse effects, of which cardiovascular adverse effects, seizures, abnormal bleeding, hyponatremia, and agranulocytosis are discussed in this review. Data regarding the incidence and risk factors are summarized, and strategies for reducing the risk of these adverse effects and managing them are suggested. Identification of risk factors, appropriate antidepressant choice, and, when possible, careful monitoring may substantially reduce the incidence of these adverse effects and the morbidity associated with them.

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Current awareness: Pharmacoepidemiology and drug safety

2005

Pharmacoepidem. Drug Safe.

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In order to keep subscribers up‐to‐date with the latest developments in their field, John Wiley & Sons are providing a current awareness service in each issue of the journal. The bibliography contains newly published material in the field of pharmacoepidemiology and drug safety. Each bibliography is divided into 20 sections: 1 Books, Reviews & Symposia; 2 General; 3 Anti‐infective Agents; 4 Cardiovascular System Agents; 5 CNS Depressive Agents; 6 Non‐steroidal Anti‐inflammatory Agents; 7 CNS Agents; 8 Anti‐neoplastic Agents; 9 Haematological Agents; 10 Neuroregulator‐Blocking Agents; 11 Dermatological Agents; 12 Immunosuppressive Agents; 13 Autonomic Agents; 14 Respiratory System Agents; 15 Neuromuscular Agents; 16 Reproductive System Agents; 17 Gastrointestinal System Agents; 18 Anti‐inflammatory Agents ‐ Steroidal; 19 Teratogens/fetal exposure; 20 Others. Within each section, articles are listed in alphabetical order with respect to author. If, in the preceding period, no publications are located relevant to any one of these headings, that section will be omitted.

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Hyponatremia Associated With Bupropion, a Case Verified by Rechallenge

Cited by 22 publications

References 3 publications

Hyponatremia Associated with Bupropion

Hyponatremia Associated with Bupropion

Medically serious adverse effects of newer antidepressants

Current awareness: Pharmacoepidemiology and drug safety

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