Hypomethylation of DYRK4 in peripheral blood is associated with increased lung cancer risk
Rong Qiao,
Qiang Zhu,
Feifei Di
et al.
Abstract:Lung cancer (LC) is the leading cause of cancer‐related deaths worldwide. It is urgent to identify new biomarkers for the early detection of LC. DNA methylation in peripheral blood has been reported to be associated with cancers. We conducted two independent case–control studies and a nested case–control study (168 LC cases and 167 controls in study Ⅰ, 677 LC cases and 833 controls in study Ⅱ, 147 precancers and 21 controls in the nested case–control study). The methylation levels of DYRK4 CpG sites were measu… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.