Hypomagnesemia: A Rare Cause of Movement Disorders, Myopathy and Vertical Nystagmus

Ray, Somdattaa; Kamath, Vikram V.; Jadhav, Swati Ramkete; Rajesh, K.N.

doi:10.1002/mdc3.13735

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2023

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Movement disorders emergencies in metabolic disorders

Álvarez Bravo,

Cots Foraster,

López Domínguez

et al. 2023

Movement Disorders Emergencies

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Movement disorders emergencies in metabolic disorders

Álvarez Bravo,

Cots Foraster,

López Domínguez

et al. 2023

Movement Disorders Emergencies

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Movement Disorders and Other Neurologic Impairment Associated With Hypomagnesemia

Ray,

Park

2023

Neur Clin Pract

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Purpose of ReviewThe objective of this study was to explore the clinical spectrum of movement disorders and associated neurologic findings in hypomagnesemia and challenges in diagnosis and treatment.Recent FindingsSixty patients were identified in the literature for analysis. Movement disorders observed were postural tremor (23.3%, n = 14), resting tremor (8.3%, n = 5), intention tremor (10%, n = 6), ataxia involving the trunk (48.3%, n = 29) or limbs (25%, n = 15) and dysarthria (21.7%, n = 13), athetosis (8.3%, n = 5), myoclonus (6.7%, n = 4), and chorea (1.8%, n = 1). Symptoms may be accompanied by downbeat nystagmus, tetany, drowsiness, vertigo, and proximal muscle weakness. Residual deficits were noted in 16 (26.67%) patients. Serum magnesium was 1.3 mg/dL or lower in 53 patients (88.3%). Imaging findings include bilateral cerebellar (20%, n = 11) and vermis hyperintensities (9.09%, n = 5) and normal imaging. Proton pump inhibitors are the commonest etiology.SummaryThe movement disorders linked with hypomagnesemia can be associated with varied neurologic symptoms. A high degree of suspicion will enable early diagnosis to prevent residual deficits.

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Hypomagnesemia: A Rare Cause of Movement Disorders, Myopathy and Vertical Nystagmus

Cited by 2 publications

References 14 publications

Movement disorders emergencies in metabolic disorders

Movement disorders emergencies in metabolic disorders

Movement Disorders and Other Neurologic Impairment Associated With Hypomagnesemia

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