Hypolipidemic effect of soluble dietary fibers prepared from Asparagus officinalis and their effects on the modulation of intestinal microbiota

Diets Enriched in Sugar, Refined, or Whole Grain Differentially Influence Plasma Cholesterol Concentrations and Cholesterol Metabolism Pathways with Concurrent Changes in Bile Acid Profile and Gut Microbiota Composition in ApoE-/- Mice

“…Both sugar- and RG-enriched diets resulted in higher relative abundance of Desulfobacterota , Campylobacterota , and Helicobacter compared to WG-enriched diet. Our finding was consistent with an animal study, which reports that dietary fiber decreases the relative abundance of Desulfobacterota and concurrently reduces circulating concentrations of TC and LDL-C .…”

“…Both sugar-and RG-enriched diets resulted in higher relative abundance of Desulfobacterota, Campylobacterota, and Helicobacter compared to WG-enriched diet. Our finding was consistent with an animal study, which reports that dietary fiber decreases the relative abundance of Desulfobacterota and concurrently reduces circulating concentrations of TC and LDL-C. 52 Helicobacter is a genus under phylum Campylobacterota, and infection with Helicobacter has been reported to decrease the cholesterol efflux capacity and results in subsequent higher concentrations of TC and LDL-C and inflammation in human subjects. 53 This is in agreement with the current study that the relative abundance of Helicobacter was positively associated with plasma concentrations of TC, LDL-C, and non-HDL-C.…”