Hypokalaemic quadriparesis: an unusual manifestation of dengue fever

Dk, Gupta; Vaish, Arvind Kumar; Arya, Rajesh Kumar; Chaudhary, Shyam Chand

doi:10.1136/bcr.12.2010.3673

Cited by 12 publications

(6 citation statements)

References 10 publications

(10 reference statements)

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“…[56] In our series, dengue virus infection was an important cause for hypokalemic paralysis. Four of our patients had hypokalemic paralysis due to dengue infection.…”

Section: Discussionmentioning

confidence: 93%

“…Viral infections, such as dengue virus and chikungunya virus, have also been reported to precipitate hypokalemic paralysis. [567] Patients with hypokalemic paralysis need a diligent search for the possible etiology and potassium replacement therapy. Majority of hypokalemic paralysis patients usually recover completely without any residual disability.…”

Section: Introductionmentioning

confidence: 99%

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Etiological spectrum of hypokalemic paralysis: A retrospective analysis of 29 patients

Garg

Malhotra

Verma

et al. 2013

Ann Indian Acad Neurol

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Background:Hypokalemic paralysis is characterized by episodes of acute muscle weakness associated with hypokalemia. In this study, we evaluated the possible etiological factors in patients of hypokalemic paralysis.Materials and Methods:We reviewed the records of 29 patients who were admitted with a diagnosis of hypokalemic paralysis. Modified Guillain-Barre´ Syndrome disability scale was used to grade the disability.Results:In this study, 15 (51.7%) patients had secondary causes of hypokalemic paralysis and 14 patients (42.3%) had idiopathic hypokalemic paralysis. Thyrotoxicosis was present in six patients (20.6%), dengue infection in four patients (13.7%), distal renal tubular acidosis in three patients (10.3%), Gitelman syndrome in one patient (3.4%), and Conn's syndrome in one patient (3.4%). Preceding history of fever and rapid recovery was seen in dengue infection-induced hypokalemic paralysis. Approximately 62% patients had elevated serum creatinine phosphokinase. All patients had recovered completely following potassium supplementation. Patients with secondary causes were older in age, had significantly more disability, lower serum potassium levels, and took longer time to recover.Conclusion:In conclusion, more than half of patients had secondary causes responsible for hypokalemic paralysis. Dengue virus infection was the second leading cause of hypokalemic paralysis, after thyrotoxicosis. Presence of severe disability, severe hypokalemia, and a late disease onset suggested secondary hypokalemic paralysis.

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“…[56] In our series, dengue virus infection was an important cause for hypokalemic paralysis. Four of our patients had hypokalemic paralysis due to dengue infection.…”

Section: Discussionmentioning

confidence: 93%

Section: Introductionmentioning

confidence: 99%

Etiological spectrum of hypokalemic paralysis: A retrospective analysis of 29 patients

Garg

Malhotra

Verma

et al. 2013

Ann Indian Acad Neurol

View full text Add to dashboard Cite

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“…The exact mechanism of hypokalemia in dengue is unclear, but there is a certain hypothesis that it can be due to a transcellular shift in response to insulin release or self-limiting transient tubular dysfunction leading to potassium excretion [ 18 ]. Further study is needed in this regard and needs to be published, as dengue is on a rising trend and neurological complications are reported frequently now [ 19 , 20 ]. Physicians in endemic areas need to open their minds to unusual presentations like hypokalemic paralysis, which could be life-threatening but easily treatable.…”

Section: Discussionmentioning

confidence: 99%

Dengue and Hypokalemic Paralysis: A Rare Association

Akhtar,

Mushtaq,

Nisar

et al. 2023

Cureus

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Dengue is one of the most common mosquito-borne viral illnesses in tropical areas, including Pakistan. Presentation varies from a self-limiting flu-like illness to life-threatening conditions like hemorrhagic shock and multi-organ dysfunction leading to death. In the absence of vomiting and diarrhea, electrolyte abnormalities are rare findings. Though Guillain-Barré syndrome is a known association of viral illnesses presenting with flaccid paralysis, there is a possibility for dengue to cause hypokalemia without apparent gut or renal losses. Dengue-associated hypokalemic paralysis is an underrecognized entity but has a favorable outcome. The clinician should suspect this in patients presenting with motor weakness in dengue-endemic areas. Neurological complications of dengue are reported frequently now, so early recognition of these neurological manifestations is needed for the successful recovery of patients. Here, we discuss a case of dengue-induced hypokalemia presenting with acute flaccid paralysis.

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“…Acute neuromuscular weakness is thought to be due to myositis, Guillain-Barré syndrome, or hypokalemic paralysis during dengue. While numerous authors have reported hypokalemic paralysis associated with dengue, most studies are based on case reports [3][4][5][6]. We present an intriguing case of hypokalemic paralysis associated with dengue in a young, pregnant female who fully recovered within 48 hours of potassium supplementation.…”

Section: Introductionmentioning

confidence: 88%

Dengue Fever-Induced Hypokalemic Paralysis in a Pregnant Patient: An Uncommon Presentation of a Common Disease

Khan,

Ali,

Ur Rehman

et al. 2023

Cureus

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Dengue fever is a globally prevalent, viral disease transmitted by Aedes mosquitoes, which is becoming increasingly common and can cause a range of symptoms, including fever, flu-like symptoms, and circulatory failure. Although it is classified as a non-neurotropic virus, research has suggested that dengue fever can also affect the nervous system and lead to conditions such as myositis, Guillain-Barré syndrome, or hypokalemic paralysis. We describe a case study of a young pregnant female with dengue-associated hypokalemic paralysis, who made a full recovery within 48 hours of receiving potassium supplementation. The case underscores the importance of recognizing and treating neurological complications of dengue fever promptly, particularly in areas where the disease is prevalent.

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Hypokalaemic quadriparesis: an unusual manifestation of dengue fever

Cited by 12 publications

References 10 publications

Etiological spectrum of hypokalemic paralysis: A retrospective analysis of 29 patients

Etiological spectrum of hypokalemic paralysis: A retrospective analysis of 29 patients

Dengue and Hypokalemic Paralysis: A Rare Association

Dengue Fever-Induced Hypokalemic Paralysis in a Pregnant Patient: An Uncommon Presentation of a Common Disease

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