Hypogonadism in leprosy males

Andrade, Luís Jesuíno de Oliveira; Oliveira, Moema Farias de; França, Larissa Santos; Sousa, Ana Libia Oliveira França de; Andrade, Cristina Setenta; Jesus, Humberto Barreto de

doi:10.9771/cmbio.v11i1.5961

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“…The social stigma attached to the disease persists despite a lot of advances in the management of the disease. The disfigurement and disabilities are the major reasons behind the social stigma of the disease 3 . The disease is caused by mycobacterium leprae and the classical sites of involvement are skin and peripheral nerves 4 .…”

Section: Introductionmentioning

confidence: 99%

Association of Testosterone Level among Lepromatous and Borderline Leprosy Male Patients: Experience of 30 Cases in Bangladesh

Mohammad

Mia

Hossain

et al. 2021

Bangladesh J. Infect. Dis.

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Background: Hormonal dysfunction is reported among the leprosy patients. Objective: The purpose of the present study was to see the association of testosterone level among male patients presented with lepromatous and borderline leprosy. Methodology: This cross-sectional study was conducted in the Leprosy Hospital, Dhaka, Bangladesh from January to December 2016 for a period of one year. All patients with a known diagnosis of leprosy under follow up at the hospital were included in the study. The serum concentration of testosterone was measured using an enzyme immunoassay technique (ELISA) (DiaMetra, Spello, Italy). Result: A total number of 30 cases of leprosy were recruited for this study. The mean with SD of the study population was 39.20±9.065 years. Among 30 cases of study population 26 cases were lepromatous leprosy patents and the rest 4 cases were Borderline Leprosy patients. The mean with the standard deviation of testosterone level in serum was 6.41±4.756 mg/dL and 4.71±2.396 mg/L in lepromatous leprosy and borderline leprosy respectively (p=0.497). Conclusion: In conclusion there is no statistically significant relationship between leprosy and testosterone; however, lower level of testosterone is found among the study population Bangladesh Journal of Infectious Diseases 2020;7(2):36-39

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Section: Introductionmentioning

confidence: 99%