Hypoglycemic and hypolipidemic properties of polysaccharides from Enterobacter cloacae Z0206 in KKAy mice

Huang, Ming; Wang, Fengqin; Zhou, Xin; Yang, Hangxian; Wang, Yizhen

doi:10.1016/j.carbpol.2014.09.008

Cited by 89 publications

(31 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These results indicate that RPs present high hypolipidaemic activities. Similarly, many saccharides, such as chitin, chitooligosaccharides and polysaccharides, from Enterobacter cloacae Z0206, Enteromorpha prolifera and Porphyra yezoensis have been reported to present hypolipidaemic activities (Huang et al, ; Qian, Zhou, & Ma, ; Teng, Qian, & Zhou, ). Glycogen, the primary intracellular storable form of glucose in animals, regulates glycogen deposition by stimulating glycogen synthase and suppressing glycogen phosphorylase; therefore, glycogen directly reflects insulin activity (Muthulakshmi & Saravanan, ).…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Hypoglycemic and hypolipidaemic activities of polysaccharides from Rhodiola rosea in KKAy mice

Mao

2017

J Food Process Preserv

View full text Add to dashboard Cite

Hyperglycaemia and hyperlipidaemia are major risk factors for developing coronary artery diseases and atherosclerosis; therefore, therapeutic drugs must be developed to prevent these conditions. Rhodiola rosea is widely used in traditional Chinese medicine. In this study, R. rosea polysaccharides (RPs) were prepared by hot water extraction, and their hypoglycaemic and hypolipidaemic activities were evaluated. KKAy mice were gavaged once daily with either distilled water (control) or RPs for 6 weeks. Intragastric RP administration improved oral glucose tolerance, decreased serum insulin levels, serum triglycerides (TG), cholesterol (TC) and low‐density lipoprotein cholesterol (LDL‐c) and increased high‐density lipoprotein cholesterol (HDL‐c). Results suggest that RPs exhibit high hypoglycaemic and hypolipidaemic activities and could be explored as possible therapeutic agents for diabetes mellitus. Practical applications Rhodiola rosea polysaccharides have high hypoglycaemic and hypolipidaemic activities and could be explored as possible therapeutic agents for diabetes mellitus and of practical industrial relevance.

show abstract

Section: Resultsmentioning

confidence: 99%

“…type 2 diabetes). Type 2 diabetes is characterised by hyperglycaemia and dyslipidaemia, which result from defects in insulin secretion and action (Huang, Wang, Zhou, Yang, & Wang, 2015).…”

Section: Introductionmentioning

confidence: 99%

Hypoglycemic and hypolipidaemic activities of polysaccharides from Rhodiola rosea in KKAy mice

Mao

2017

J Food Process Preserv

View full text Add to dashboard Cite

show abstract

“…1 More than 90% of diabetic patients are diagnosed as non-insulin-dependent (type 2 DM), which is characterized by hyperglycemia and dyslipidemia caused by the defects of either insulin secretion or action. 2 Many studies reported that DM impaired sperm parameters and decreased testosterone serum levels. [3][4][5][6][7][8] Talebi et al 6 reported that vitamin C attenuated the detrimental effects of DM on sperm parameters, chromatin quality, and rate of apoptosis in mice; Gonzales et al 7 found that the mixture of extracts from Peruvian plants (black maca and yacon) improved sperm count and reduced glycemia in mice with streptozotocininduced diabetes.…”

Section: Introductionmentioning

confidence: 99%

Peach gum polysaccharides improve the spermatogenesis of KKAy mice with impaired reproduction system

Wang

Song³

et al. 2017

Am J Reprod Immunol

View full text Add to dashboard Cite

show abstract

“…They have a variety of activities, such as anti-tumor [1], immune regulation [2], hypoglycemic [3], antioxidant [4] etc. Since there is a polysaccharide with a wide variety of biologically active, and it is widely used in clinical and functional foods, so polysaccharide becomes increasingly important.…”

Section: Introductionmentioning

confidence: 99%

Research Progress of Low Molecular Weight Polysaccharides

Xu¹,

Liu²,

Li³

et al. 2017

dteees

View full text Add to dashboard Cite

Abstract. In this paper, lots of low molecular weight polysaccharides were reviewed. The advances of the extraction, purification, biological activity and structural changes of low molecular weight polysaccharides were detailed. And future research directions were outlooked, the article noted that future research should focus on the microscopic mechanism and establish appropriate physical and mathematical models. Low molecular weight polysaccharide can be applied to the new injection agent aspects of clinical anti-tumor and lowering blood pressure.

show abstract

Hypoglycemic and hypolipidemic properties of polysaccharides from Enterobacter cloacae Z0206 in KKAy mice

Cited by 89 publications

References 42 publications

Hypoglycemic and hypolipidaemic activities of polysaccharides from Rhodiola rosea in KKAy mice

Hypoglycemic and hypolipidaemic activities of polysaccharides from Rhodiola rosea in KKAy mice

Peach gum polysaccharides improve the spermatogenesis of KKAy mice with impaired reproduction system

Research Progress of Low Molecular Weight Polysaccharides

Contact Info

Product

Resources

About