Hypoglycemia in Infants and Children

Hoe, Francis M.

doi:10.1016/j.yapd.2008.07.008

Cited by 26 publications

(14 citation statements)

References 52 publications

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“…1617 Glycogen storage disease and inborn errors of metabolism, hypopituitarism, ingestions, and sepsis are some hypoglycemia etiologies occurring during infancy and toddler years. 18 Consistently, Chen et al 19 in a study from Taiwan reported hypoglycemia as an infrequent cause of seizure.…”

Section: Discussionmentioning

confidence: 84%

Etiology of the Neonatal Seizures: An Epidemiological Study

Zafari

Pajouhandeh

Ahmadi

2019

Int Clin Neurosci J

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Background: Neonatal seizure is a rare neurologic condition. The current study aimed at determining the etiology of neonatal seizure. Methods: The current study evaluated the data of 100 neonates who were hospitalized at neonatal intensive care unit (NICU) during 2015-2017. A pediatric neurologist made the final diagnosis of seizure. Patients’ medical records were used to review neonatal seizure variables. SPSS (version 16) was used to perform the statistical analyses. Results: The current study enrolled 100 newborns (41% female) admitted to the NICU following the first episode of seizure and the body temperature of 36.8-39.2°C (mean: 37.2°C). Of 100 participants, 94 (94%) had acute symptomatic seizure and 6 (6%) were compatible with neonatal epilepsy syndrome criteria. According to the results, the commonest etiologies were the neonatal encephalopathy and hypoxic-ischemic encephalopathy constituting 82% of participants. Conclusion: The consequences of acute symptomatic seizures in neonates are determined mainly by the etiology of the seizures. Seizure burden and use of anti-seizure drugs may also have some impact, but this has yet to be fully defined.

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Section: Discussionmentioning

confidence: 84%

Etiology of the Neonatal Seizures: An Epidemiological Study

Zafari

Pajouhandeh

Ahmadi

2019

Int Clin Neurosci J

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“…Hypoglycaemia in infants and children can have multiple causes 11. In this case, normal chromatography of free amino-acids, organic acids and sugars as well as normal levels of lactate and fasting insulin ruled out disorders of carbohydrate, fatty-acid and amino-acid metabolism as well as hyperinsulinism.…”

Section: Discussionmentioning

confidence: 91%

Septo-optic dysplasia: fitting the pieces together

et al. 2013

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A 7-year-old boy was admitted for a general tonic-clonic seizure with severe hypoglycaemia (1.39 mmol/l). His medical history was remarkable for a congenital left eye strabismus, unilateral cryptorchidism and three previous episodes of hypoglycaemic seizures with inconclusive metabolical and neurological investigations. Physical examination revealed a hoarse tone voice, dry skin, cold extremities and height in the third percentile (target height between 50th and 85th percentile). Left wrist radiography revealed a bone age of 4.5 years ±6 months Laboratory studies confirmed growth hormone deficiency and central hypothyroidism. The brain MRI showed an ectopic neurohypophysis. Neuroophthalmology investigation revealed left optic nerve hypoplasia and septo-optic dysplasia was then diagnosed. Thyroid and recombinant growth hormone replacement were started showing clinical improvement. A detailed clinical history and a careful physical examination in children presenting with multiple clinical signs of hypopituitarism may lead to a timely diagnosis, avoiding clinical morbidity associated to untreated hormonal abnormalities.

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“…During fasting, stored energy sources such as glycogen, triglyceride and protein are converted to glucose, fatty acids and ketones (fasting systems). However, in infants the energy stores are not plentiful and fasting systems are not totally effective (Hoe 2008). Thus, infant easily become hypoglycemic upon fasting.…”

Section: 4 Discussionmentioning

confidence: 99%

A Short-Term Fasting in Neonates Induces Breathing Instability and Epigenetic Modification in the Carotid Body

Shirahata

Tang

Kostuk

2015

Advances in Experimental Medicine and Biology

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The respiratory control system is not fully developed in newborn, and data suggest that adequate nutrition is important for the development of the respiratory control system. Infants need to be fed every 2–4 h to maintain appropriate energy levels, but a skip of feeding can occur due to social economical reasons or mild sickness of infants. Here, we asked questions if a short-term fasting (1) alters carotid body (CB) chemoreceptor activity and integrated function of the respiratory control system; (2) causes epigenetic modification within the respiratory control system. Mouse pups (

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Hypoglycemia in Infants and Children

Cited by 26 publications

References 52 publications

Etiology of the Neonatal Seizures: An Epidemiological Study

Etiology of the Neonatal Seizures: An Epidemiological Study

Septo-optic dysplasia: fitting the pieces together

A Short-Term Fasting in Neonates Induces Breathing Instability and Epigenetic Modification in the Carotid Body

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