Hypoglycaemic alcoholic ketoacidosis: a forgotten medical emergency

Caulkins, Clayton; Desai, Premal B.; Feghaly, Julien; Chadaga, Rajagopal

doi:10.12968/hmed.2020.0105

Cited by 2 publications

(1 citation statement)

References 5 publications

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“…Therefore, hypoglycemic alcoholic ketoacidosis is sometimes regarded as a forgotten medical emergency. [ 2 ] Also, it is well known that hypoglycemia is induced by the overuse of anti-diabetic drugs such as insulin preparation and sulfonylurea and various disorders such as insulinoma, insulin autoimmune syndrome, and adrenal insufficiency. [ 3 ] In addition, hypoglycemia leads to various clinical problems such as acute coronary syndrome and fundus hemorrhage.…”

Section: Introductionmentioning

confidence: 99%

Case report of severe hypoglycemic alcoholic ketoacidosis: A possible pitfall in diagnosis of ketoacidosis

et al. 2022

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Backgrounds: Hypoglycemic alcoholic ketoacidosis is known to be one of the emergent diseases but its frequency is very low compared to hyperglycemic ketoacidosis or hyperosmolar hyperglycemic syndrome observed in subjects with diabetes mellitus. Case presentation: We experienced a case who had alcoholic ketoacidosis and severe hypoglycemia after drinking too much alcohol without taking enough food for a long period of time. In this subject, plasma glucose level was as low as 25 mg/dL, and ketone bodies, especially 3-hydroxybutyrate, were markedly increased. In addition, in blood gas analysis, severe acidosis was observed and anion gap was increased. These points were compatible with hypoglycemia alcoholic ketoacidosis. Conclusions: When we examine subjects with ketoacidosis and hypoglycemia, we should bear in mind the possibility of hypoglycemic alcoholic ketoacidosis especially in subjects who drink too much alcohol without taking enough food for a long period of time.

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Section: Introductionmentioning

confidence: 99%

Case report of severe hypoglycemic alcoholic ketoacidosis: A possible pitfall in diagnosis of ketoacidosis

et al. 2022

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Successfully managed alcoholic ketoacidosis with sepsis leading to multiple organ dysfunction syndrome: a case report

Roy,

Roy

2024

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We present the case of a 28-year-old male with a history of alcohol dependency and smoking, who presented with chest pain, shortness of breath, and altered sensorium. He exhibited severe metabolic acidosis, hypoglycemia, low platelet count, and acute kidney injury. Alcoholic ketoacidosis was suspected due to ketonuria, metabolic acidosis, and ketonemia, compounded by electrolyte abnormalities and radiographic findings of pneumonia. Prompt intervention included intravenous fluids, electrolyte correction, thiamine supplementation, broad-spectrum antibiotics, and diuretics. Thiamine played a pivotal role in the patient’s recovery, with significant improvement in consciousness observed within a day. After six days, the patient was discharged in stable condition, with normal renal and hepatic function at follow-up. This case emphasizes the need for early recognition and comprehensive management in alcoholic ketoacidosis, highlighting thiamine’s crucial role in treatment success.

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Hypoglycaemic alcoholic ketoacidosis: a forgotten medical emergency

Cited by 2 publications

References 5 publications

Case report of severe hypoglycemic alcoholic ketoacidosis: A possible pitfall in diagnosis of ketoacidosis

Case report of severe hypoglycemic alcoholic ketoacidosis: A possible pitfall in diagnosis of ketoacidosis

Successfully managed alcoholic ketoacidosis with sepsis leading to multiple organ dysfunction syndrome: a case report

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