Hypoglycaemia was common in acute gastroenteritis in a prospective hospital‐based study, but electrolyte imbalances were not

Qadori, Mohammed; Flem, Elmira; Bekkevold, Terese; Døllner, Henrik; Gilje, Ann Marit; Rojahn, A; Størdal, Ketil

doi:10.1111/apa.14318

Cited by 12 publications

(9 citation statements)

References 26 publications

(24 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The majority of children were more likely to present at the hospital early with a length of illness less than 2 days, which was also similar to ndings in previous studies [6, 7]. Consistent with previous pediatric studies [7,11,12], most patients (74.9%) in this study had mild-to-moderate dehydration at presentation. Viruses have been found to be the main cause of AGE in children [1,16].…”

Section: Discussionsupporting

confidence: 91%

See 1 more Smart Citation

Dysnatremia and Subsequent Serum Sodium Level Changes Following Various Intravenous Treatments in Infants with Acute Gastroenteritis

Sakkongviseth,

Sommai,

Sumboonnanonda

et al. 2023

Preprint

View full text Add to dashboard Cite

Purpose Acute gastroenteritis (AGE) is one of the main causes of electrolyte imbalance in infants. We aimed to determine the incidence of and factors associated with early dysnatremia and establish the ideal intravenous (IV) treatment scheme. Methods The records of hospitalized infants aged 1–12 months with community-acquired AGE between January 2017 and March 2021 were retrospectively reviewed. Factors associated with early dysnatremia were analyzed by multivariable logistic regression analysis. Subsequent serum sodium levels 4–24 hours after IV fluid treatments, which were categorized into 3 groups, were determined in the subgroup of infants with early isonatremia. Results In total, 347 infants with a median age of 8.0 (5.0, 10.0) months were included. The incidence of early dysnatremia was 14.4% (hyponatremia 12.4% and hypernatremia 2.0%). Severe dehydration was associated with early dysnatremia (p = 0.048). Among 70 infants with early isonatremia, the median serum sodium change was highest in the D-5NS group, with changes of + 3 (0.5, 5), + 1 (-2, 2) and − 2.5 (-4, 2.3) mmol/L in infants who received D5-NS, D-1/2NS, and D5-1/3 − 1/5NS, respectively (p = 0.003). Four out of 39 infants (10.3%) developed hyponatremia while receiving D5-1/2NS. None of those who received D5-NS developed subsequent dysnatremia. Conclusions The incidence of early dysnatremia among infants with AGE was 14.4%. Severe dehydration was a strong factor associated with early dysnatremia, so electrolyte levels need to be assessed. The use of isotonic solution did not promote acquired dysnatremia. We therefore recommend that isotonic solution be considered for infants with AGE.

show abstract

Section: Discussionsupporting

confidence: 91%

“…This study demonstrated a predominance of males (59.4%), as in previous pediatric series [7,8,11,12]. The majority of children were more likely to present at the hospital early with a length of illness less than 2 days, which was also similar to ndings in previous studies [6, 7].…”

Section: Discussionsupporting

confidence: 91%

Dysnatremia and Subsequent Serum Sodium Level Changes Following Various Intravenous Treatments in Infants with Acute Gastroenteritis

Sakkongviseth,

Sommai,

Sumboonnanonda

et al. 2023

Preprint

View full text Add to dashboard Cite

show abstract

“…Moreover, children from our series had significant glucose, electrolyte and acid-base abnormalities, which is not that common according to other studies. 21,22 Qadori et al 26 found an association between the duration of vomiting and the risk of hypoglycemia, which could explain hypoglycemia episodes in our patients, too.…”

Section: Discussionsupporting

confidence: 54%

Ukrainian War Refugee Children With Particularly Severe Viral Infections: A Case Series Report

Pluta,

Karny,

Lipińska

et al. 2023

Pediatric Infectious Disease Journal

View full text Add to dashboard Cite

The humanitarian crisis in Ukraine in 2022 led to a massive migration of refugees to Poland. Immigrant children, living in overcrowded humanitarian hubs, were exposed to multiple stressful factors likely affecting their immune systems. This case series study aimed to describe a particularly severe course of common viral infections, in Ukrainian refugee children. We present 2 case series of Ukrainian refugee children: 5 hospitalized due to either adenovirus (AdV) and 8 with rotavirus (RV) infection, admitted within 3 months in each case series, recruited retrospectively. Most patients lived in humanitarian hubs and were neglected on admission (dehydrated, with poor hygiene and anxious). All RV infection cases had symptoms of severe gastroenteritis requiring intravenous rehydration. Metabolic acidosis was present in 6 children, and hypoglycemia in 4 participants. None of them were vaccinated against RV. All children with AdV infection had prolonged fever, dyspnea requiring oxygen therapy and hyperinflammation. In 2 AdV infection cases with no clinical improvement and increasing inflammatory markers, intravenous immunoglobulins and glucocorticosteroids were used. The combination of stressful factors and living in overcrowded hubs during the high prevalence of viral infections led to a particularly severe course of viral infections in Ukrainian refugee children.

show abstract

“…BUN, creatinine, and blood gases (pH, serum bicarbonate) were discovered to be useful clinical markers to determine dehydration and severity in children with acute gastroenteritis (17)(18)(19). Higher levels of creatinine, BUN, potassium, and lower glucose, pH, bicarbonate, albumin levels in severe group were related to the serious dehydration and acidosis.…”

Section: Discussionmentioning

confidence: 99%

Role of neutrophil-to-lymphocyte, mean platelet volume-to-platelet and platelet-to-lymphocyte ratios as predictors of disease severity in Rotavirus gastroenteritis

Güven

2022

Journal of Medicine and Palliative Care

View full text Add to dashboard Cite

Amaç: Gelişmekte olan ülkelerde Rotavirus gastroenteriti (RG) günümüzde bile en yaygın ölüm ve morbidite nedenlerinden biridir. Sonuç olarak, klinisyenler RG’nin varlığını ve ciddiyetini tespit etmede son derece uyanık olmalıdır. Bu çalışmanın amacı, nötrofil lenfosit oranı (NLO), ortalama trombosit hacmi trombosit oranı (OTH/T) ve trombosit lenfosit oranı (TLO) dahil olmak üzere tam kan sayımlarını analiz ederek RG şiddetinin öngörücülerini belirlemekti. Gereç ve Yöntem: Veriler, Ocak 2019 ile Aralık 2021 tarihleri arasında Sağlık Bilimleri Üniversitesi, Ankara Atatürk Sanatoryum Eğitim ve Araştırma Hastanesinde de RG tanısı konan 456 çocuğun tıbbi kayıtlarından ve aynı yaştaki sağlıklı çocukların tıbbi kayıtlarından geriye dönük olarak elde edildi. Hastalık şiddetini; şiddetli veya hafif kategorize etmek için Vesikari skoru kullanıldı. Değişkenlerin hastalık şiddeti üzerindeki prognostik etkileri gruplar arasında karşılaştırıldı. Bulgular: Çalışmaya RG’lı 456 çocuk dahil edildi. Bunlardan iki yüz otuz ikisi şiddetliydi; 126 erkek; medyan yaş: 1,24 (0,41-2,36) yıl, 224’ü şiddetli değil; 126 erkek; medyan yaş 1,52 (1,01-2,84) yıldı. Hastanede medyan kalış süresi ağır grup için 5 (4-7) gün ve ağır olmayan grup için 2 (0-3) gündü (p

show abstract

Hypoglycaemia was common in acute gastroenteritis in a prospective hospital‐based study, but electrolyte imbalances were not

Abstract: Hypoglycaemia was common in acute gastroenteritis, but major electrolyte disturbances were infrequent.

Cited by 12 publications

References 26 publications

Dysnatremia and Subsequent Serum Sodium Level Changes Following Various Intravenous Treatments in Infants with Acute Gastroenteritis

Dysnatremia and Subsequent Serum Sodium Level Changes Following Various Intravenous Treatments in Infants with Acute Gastroenteritis

Ukrainian War Refugee Children With Particularly Severe Viral Infections: A Case Series Report

Role of neutrophil-to-lymphocyte, mean platelet volume-to-platelet and platelet-to-lymphocyte ratios as predictors of disease severity in Rotavirus gastroenteritis

Contact Info

Product

Resources

About