Hypofunction of the adrenals in early life

Jaudon, Joseph C.

doi:10.1016/s0022-3476(46)80003-9

Cited by 41 publications

(8 citation statements)

References 27 publications

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“…but the presence of persistent vomiting and feeding difficulty with periods of dehydration and persistent failure to thrive should lead to investigation of the serum and urinary electrolyte levels on several occasions. Jaudon (1946) has suggested that …”

Section: Discussionmentioning

confidence: 99%

Two Cases of Adrenal Hyperplasia with Adrenal Cortical Insufficiency

France¹,

Neill²

1951

Archives of Disease in Childhood

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Section: Discussionmentioning

confidence: 99%

Two Cases of Adrenal Hyperplasia with Adrenal Cortical Insufficiency

France¹,

Neill²

1951

Archives of Disease in Childhood

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“…The third patient had congenital glaucoma. 1 This work was made possible by a grant from the American Cancer Society for studies on the relationship of the pituitary hormones, thyroid hormone, and the steroid hormones of the adrenal glands and gonads to normal and abnormal growth, and by a grant from the Commonwealth Fund for the study of endocrine problems in childhood. 2 These were treated under the supervision of Drs.…”

Section: Methodsmentioning

confidence: 99%

“…The anatomical peculiarities of the adrenal cortex in this period are well known. Jaudon (1) has suggested that transient deficiencies in adrenocortical function occur in the newborn period. However, few experimental studies have been reported.…”

mentioning

confidence: 99%

Adrenocortical Control of Sodium and Potassium Excretion in the Newborn Period 1

Klein¹

1951

J. Clin. Invest.

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“…The negative sodium balance, as it has been pointed out by Sulyok (1971), could be due to a temporary adrenocortical hypofunction suggested by several authors (Joudon, 1948;Provenzano, 1950;Klein, 195\\Lenman, 1953;Visseret al, 1964). Recent studies performed on term and preterm infants, however, have demonstrated high plasma aldosterone concentration and an increased aldoste rone secretion when the sodium intake of the newborn infants is reduced {Weldon Beitnis et al, 1972;Siegel et al, 1974).…”

Section: Discussionmentioning

confidence: 87%

Plasma Osmolality in the Early and Late Neonatal Period with Particular Reference to Low Birth Weight Infants

Mestyán¹,

Horváth²,

Mestyán³

1976

Neonatology

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Data on postnatal changes of plasma osmolality were collected on two groups of newborn infants. Group I consisted of 114 normal full-term infants in whom measurements were performed in cord blood and peripheral venous blood at 12, 24 and 48 h after birth. It has been found that plasma osmolality does not change within the first 48 h, but is maintained at the level of cord plasma. The infants comprising group II were admitted to a referral unit at different postnatal ages for observation or treatment of transient neonatal disturbances. The majority of the infants and particularly those followed through the late neonatal period were low birth weight infants. Neither of the infants studied required intravenous therapy known to affect plasma osmolality. Blood samples were taken at admission and at different time intervals thereafter. Time at which blood was withdrawn varied in the individual infant. In 95 plasma samples, besides osmolality, sodium concentration was also measured. In this group of infants, after the first 3 days, plasma osmolality steadily fell with postnatal age reaching a minimum between 18–21 days. The fall in plasma osmolality was accompanied by a parallel decline of plasma sodium. The two variables were significantly correlated. It is concluded that the decrease in plasma osmolality of low birth weight infants represents profound adaptive changes of osmolal homeostasis in the late neonatal period. The possible mechanisms underlying the total osmotic pressure changes, such as expansion of extracellular volume, sodium loss, immaturity of kidney function are discussed.

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Hypofunction of the adrenals in early life

Cited by 41 publications

References 27 publications

Two Cases of Adrenal Hyperplasia with Adrenal Cortical Insufficiency

Two Cases of Adrenal Hyperplasia with Adrenal Cortical Insufficiency

Adrenocortical Control of Sodium and Potassium Excretion in the Newborn Period 1

Plasma Osmolality in the Early and Late Neonatal Period with Particular Reference to Low Birth Weight Infants

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