Hypofractionated Radiation Therapy for Prostate Cancer: More Food for Thought From Recent Trial

Alpha/beta (α/β) ratio for prostate cancer derived from external beam radiotherapy and brachytherapy boost

“…Correspondence regarding the trial addressed the apparent discord between the trial's outcome and the increasing evidence in favour of hypofractionation. [23][24][25] In fact, the observed near-isoeffectiveness of these two dose fractionations is less unexpected, given our estimate: a/b 5 7.7 Gy yields an LQED 2Gy of 75.3 Gy for the hypofractionated arm, slightly ,76 Gy delivered conventionally.…”