Hypocholesterolemic potential and bioactivity spectrum of an exopolysaccharide from a probiotic isolate Lactobacillus paracasei M7

Bhat, Bilal A.; Bajaj, Bijender Kumar

doi:10.1016/j.bcdf.2019.100191

Cited by 55 publications

(32 citation statements)

References 39 publications

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“…Very limited researches has been conducted on cholesterol lowering properties but in recent studies aiming at lowering blood cholesterol level through EPS of probiotic origin gained significant attention. The EPS produced by Lactobacillus paracasei M7 reported the reduction of cholesterol level (30 μg at 25°C for 20 min) to 70.78% in-vitro with optimum dose of 0.1% EPS [115]. The EPS derived from Lactobacillus plantarum RJF4 was shown to reduce the cholesterol to 42.24% [1].…”

Section: Hypocholestrolemic and Antidiabetic Activitymentioning

confidence: 97%

Exopolysaccharides from probiotic bacteria and their health potential

Angelin

Kavitha

2020

International Journal of Biological Macromolecules

315

225

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Exopolysaccharides (EPS) are extracellular macromolecules excreted as tightly bound capsule or loosely attached slime layer in microorganisms. They play most prominent role against desiccation, phagocytosis, cell recognition, phage attack, antibiotics or toxic compounds and osmotic stress. In the last few decades, natural polymers have gained much attention among scientific communities owing to their therapeutic potential. In particular the EPS retrieved from probiotic bacteria with varied carbohydrate compositions possess a plenty of beneficial properties. Different probiotic microbes have unique behavior in expressing their capability to display significant health promoting characteristics in the form of polysaccharides. In this new era of alternative medicines, these polysaccharides are considered as substitutes for synthetic drugs. The EPS finds applications in various fields like textiles, cosmetics, bioremediation, food and therapeutics. The present review is focused on sources, chemical composition, biosynthetic pathways of EPS and their biological potential. More attention has been given to the scientific investigations on antimicrobial, antitumor, anti-biofilm, antiviral, anti-inflammatory and immunomodulatory activities.

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Section: Hypocholestrolemic and Antidiabetic Activitymentioning

confidence: 97%

Exopolysaccharides from probiotic bacteria and their health potential

Angelin

Kavitha

2020

International Journal of Biological Macromolecules

315

225

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“…At the same time, the EPS also have a significant role as prebiotics and can enhance probiotic colonization in the gut. They have also been used as immunomodulatory, immunostimulatory, antidiabetic, and hypocholesterolemic agents [87,88].…”

Section: Fermented Fruit and Vegetable Beveragesmentioning

confidence: 99%

Non-Dairy Fermented Beverages as Potential Carriers to Ensure Probiotics, Prebiotics, and Bioactive Compounds Arrival to the Gut and Their Health Benefits

et al. 2020

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In alignment with Hippocrates’ aphorisms “Let food be your medicine and medicine be your food” and “All diseases begin in the gut”, recent studies have suggested that healthy diets should include fermented foods to temporally enhance live microorganisms in our gut. As a result, consumers are now demanding this type of food and fermented food has gained popularity. However, certain sectors of population, such as those allergic to milk proteins, lactose intolerant and strict vegetarians, cannot consume dairy products. Therefore, a need has arisen in order to offer consumers an alternative to fermented dairy products by exploring new non-dairy matrices as probiotics carriers. Accordingly, this review aims to explore the benefits of different fermented non-dairy beverages (legume, cereal, pseudocereal, fruit and vegetable), as potential carriers of bioactive compounds (generated during the fermentation process), prebiotics and different probiotic bacteria, providing protection to ensure that their viability is in the range of 106–107 CFU/mL at the consumption time, in order that they reach the intestine in high amounts and improve human health through modulation of the gut microbiome.

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“…On the other hand, pharmacological approaches, generally cholesterol-lowering drugs (i.e., statins), are still applied, despite the side effects. Recently, among dietary interventions, fermented dairy foods and/or probiotics, as well as specific microbial molecules such as EPS, have been shown a potential role in CVDs management for their lowering-cholesterol activity [ 133 ].…”

Section: Eps and Health Benefitsmentioning

confidence: 99%

“…Recently, EPS from Lcb. paracasei M7 showed higher in vitro cholesterol-lowering activity (70.78%) [ 133 ].…”

Section: Eps and Health Benefitsmentioning

confidence: 99%

Lactic Acid Bacteria Exopolysaccharides Producers: A Sustainable Tool for Functional Foods

Prete

Alam

Perpetuini

et al. 2021

Foods

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Lactic acid bacteria (LAB) used in the food industry, mainly for the production of dairy products, are able to synthetize exopolysaccharides (EPS). EPS play a central role in the assessment of rheological and sensory characteristics of dairy products since they positively influence texture and organoleptic properties. Besides these, EPS have gained relevant interest for pharmacological and nutraceutical applications due to their biocompatibility, non-toxicity and biodegradability. These bioactive compounds may act as antioxidant, cholesterol-lowering, antimicrobial and prebiotic agents. This review provides an overview of exopolysaccharide-producing LAB, with an insight on the factors affecting EPS production, their dairy industrial applications and health benefits.

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Hypocholesterolemic potential and bioactivity spectrum of an exopolysaccharide from a probiotic isolate Lactobacillus paracasei M7

Cited by 55 publications

References 39 publications

Exopolysaccharides from probiotic bacteria and their health potential

Exopolysaccharides from probiotic bacteria and their health potential

Non-Dairy Fermented Beverages as Potential Carriers to Ensure Probiotics, Prebiotics, and Bioactive Compounds Arrival to the Gut and Their Health Benefits

Lactic Acid Bacteria Exopolysaccharides Producers: A Sustainable Tool for Functional Foods

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